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S1764

Sigma-Aldrich

Complement sera human

lyophilized powder

Synonyme(s) :

Human Serum Complement

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About This Item

Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61
Source biologique:
human
Origine:
USA origin
Forme:
lyophilized powder
Conditions d'expédition:
dry ice
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Source biologique

human

Niveau de qualité

Forme

lyophilized powder

Origine

USA origin

Technique(s)

cell culture | mammalian: suitable

Impuretés

virus, tested

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Complement serum is prepared from pooled human plasma and lyophilized from the amount of serum indicated on the label.

Application

Complement sera human has been used:
  • to incubate DLD-1 or SW-620 cells to quantify C5a release
  • in multiplex bead antibody-binding assay to assay C3d
  • in complement-dependent cytotoxicity assay

Complement sera human has been used:
  • to incubate DLD-1 or SW-620 cells to quantify C5a release[1]
  • in multiplex bead antibody-binding assay to assay C3d[2]
  • in complement-dependent cytotoxicity assay[3]

The activity of complement sera can be determined by hemolytic assays in vitro. [4]

Forme physique

Lyophilized powder from indicated amount of serum

Remarque sur l'analyse

Hemolytic titer (CH50 units per ml) is determined by method of Kabat and Mayer. Actual titer given on label.

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d′importation et d′exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L′acheteur (c′est-à-dire l′utilisateur FINAL) est tenu d′obtenir une autorisation d′importation auprès du ministère français de la recherche, mentionné à l′article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l′autorisation d′importation requise.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Lisa Tomasi et al.
Open forum infectious diseases, 9(11), ofac554-ofac554 (2022-12-06)
The basis of the less severe clinical presentation of coronavirus disease 2019 (COVID-19) in children as compared with adults remains incompletely understood. Studies have suggested that a more potent boosting of immunity to endemic common cold coronaviruses (HCoVs) may protect
Anaïs Thiriard et al.
Frontiers in immunology, 14, 1107156-1107156 (2023-04-04)
To comprehensively analyze the quality of the antibody response between children with Multisystem inflammatory syndrome (MIS-C) and age-matched controls at one month after SARS-CoV-2 exposure, and infected in the same time-period. Serum from 20 MIS-C children at admission, and 14
Helen Kotanides et al.
Cancer immunology research, 8(10), 1300-1310 (2020-09-03)
The programmed cell death protein 1 receptor (PD-1) and programmed death ligand 1 (PD-L1) coinhibitory pathway suppresses T-cell-mediated immunity. We hypothesized that cotargeting of PD-1 and PD-L1 with a bispecific antibody molecule could provide an alternative therapeutic approach, with enhanced
Chiaki Kawabata et al.
Biological & pharmaceutical bulletin, 44(2), 219-224 (2021-02-02)
Baculovirus vectors (BVs) are safely able to transduce foreign genes and express them in mammalian cells. However, the transduction activity of BVs is strongly reduced by the attack of serum complement, which is one of the major obstacles in the
Yui Suzuki et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(14), 4388-4399 (2019-04-26)
The anti-CCR4 mAb, mogamulizumab, offers therapeutic benefit to patients with adult T-cell leukemia-lymphoma (ATL), but skin-related adverse events (AE) such as erythema multiforme occur frequently. The purpose of this study was to determine the mechanisms by which mogamulizumab causes skin-related

Questions

  1. Hello. This product is a pool of how many donnors ? Thanks for your help

    1 answer
    1. The donor pool size varies from lot to lot. Historical data indicates that the raw material is typically derived from a pool of 12 - 15 donors.

      Helpful?

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