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Key Documents

S0615

Sigma-Aldrich

FBS Superior

Supplemented FBS, EU approved

Synonyme(s) :

FBS, FCS, Fetal Bovine Sera, Fetal Bovine Serum, Supplemented FCS

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About This Item

Code UNSPSC :
12352207
Nomenclature NACRES :
NA.71

Source biologique

bovine fetus

Niveau de qualité

Stérilité

sterile-filtered

Gamme de produits

FBS Select

Qualité

EU approved

Composition

hemoglobin, <50 mg/dL

Origine

non-USA origin

Impuretés

≤25 EU/mL endotoxin

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Fetal bovine serum (FBS), a traditional serum supplement, is used in animal cell culture media. It is obtained from the fetus of the cow.

Application

FBS Superior has been used:
  • as a component of differentiation medium, growth medium, induction medium, and Dulbecco′s modified Eagle medium (DMEM) for murine thermogenic adipocytes culture
  • as a component of the culture medium along with DMEM high glucose (HG) for cell viability check
  • as a component of minimum essential medium Eagle (MEM) to cultivate Caco-2 human colon adenocarcinoma cells

Actions biochimiques/physiologiques

Fetal bovine serum(FBS) Superior is a South American source of FBS supplemented with various growth-promoting compounds to allow for a more consistent product. This supplementation can reduce or eliminate the need to test multiple batches on specific cell lines. FBS Superior can be used just like regular FBS, delivers nutrients, growth, and attachment factors, and protects cells from oxidative damage and apoptosis by mechanisms that are difficult to reproduce in serum-free media (SFM) systems.

Fetal bovine serum (FBS) comprises growth factors (GFs) and other elements that are required for the expansion, maintenance, attachment, and proliferation of adipose-derived stromal cells (ASC) in vitro.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Carlo E A Jochems et al.
Alternatives to laboratory animals : ATLA, 30(2), 219-227 (2002-04-25)
Fetal bovine serum (FBS) is a common component of animal cell culture media. It is harvested from bovine fetuses taken from pregnant cows during slaughter. FBS is commonly harvested by means of a cardiac puncture without any form of anaesthesia.
Ali Samadi et al.
Advanced biomedical research, 10, 4-4 (2021-05-08)
Wounds have a bad prognostic nature and excessive discharges whose regular wound dressings are ineffective. Hydrogels are the best candidates for dressing such wounds due to their high water content and ability to exchange substances. Accordingly, the purpose of this
Carla Dessels et al.
Frontiers in cell and developmental biology, 4, 115-115 (2016-11-02)
Adipose-derived stromal cells (ASCs) are being used extensively in clinical trials. These trials require that ASCs are prepared using good manufacturing practices (GMPs) and are safe for use in humans. The majority of clinical trials in which ASCs are expanded
Arjen J Jakobi et al.
Nature communications, 11(1), 440-440 (2020-01-25)
p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular determinants that govern PB1 domain filament formation in vitro remain to be determined and
Giftson J Senapathy et al.
Molecules (Basel, Switzerland), 25(21) (2020-10-28)
Worldwide, lung cancer remains one of the leading cancers with increasing mortality rates. Though chemotherapy for lung cancer is effective, it is always accompanied by unavoidable and grave side effects. Photodynamic therapy (PDT), using novel photosensitizers, is an advanced treatment

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