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RAB0810

Sigma-Aldrich

Mouse Il18 / Interleukin-18 ELISA Kit

for serum, plasma and cell culture supernatants

Synonyme(s) :

IFN-gamma-inducing factor, IL-18, Interleukin-18 

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

mouse

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.15 ng/mL
standard curve range: 0.205-50 ng/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

mouse ... Il18(16173)

Description générale

Interleukin-18 (IL-18) belongs to the IL-1 family of cytokines. It is synthesized as an inactive precursor and converted to the active form by caspase-1. IL-18 is involved in the synthesis of interferon-γ (IFN-γ) and IL-13 from T-cells and natural killer (NK) cells. It is a proinflammatory cytokine that aids in the activation of NK cells and T helper 1 cell response. The antibody pair provided in this kit recognizes mouse interleukin 18.
The antibody pair provided in this kit recognizes Mouse Interleukin 18.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse Il18 / Interleukin-18 ELISA Kit has been used to detect interleukin-18 in serum samples.

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Réf. du produit
Description
FDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS
  • RABSTOP3ELISA Stop Solution (Item I)FDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)FDS
  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)FDS
  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Charles A Dinarello et al.
Frontiers in immunology, 4, 289-289 (2013-10-12)
Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly
T Yoshimoto et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(24), 13962-13966 (1999-11-26)
IL-18 is a proinflammatory cytokine that plays an important role in natural killer cell activation and T helper 1 (Th1) cell responses. Mast cells and basophils are major inducers and effectors of allergic inflammation. Here we show that basophils and
Zufeng Ding et al.
Biochemical and biophysical research communications, 451(4), 637-643 (2014-08-19)
Lectin-like oxidized low-density lipoprotein scavenger receptor-1 (LOX-1) is known to be involved in many pathophysiological events, such as inflammation. To clarify the role of LOX-1 in mtDNA damage and NLRP3 inflammasome activation, we studied wild-type (WT) and LOX-1 knockout (KO)
Jin-Mei Chen et al.
Cytokine, 119, 113-118 (2019-03-25)
Recent studies have provided overwhelming evidence of the involvement of microglia-related molecular networks in the pathogenesis of Alzheimer's diseases (AD). The potential involvement of pro-inflammatory cytokines interleukin (IL)-18, IL-23 and IL-17 on amyloid (Aβ) clearance is still unclear. In this
Benjamin Uzan et al.
EMBO molecular medicine, 6(6), 821-834 (2014-04-30)
Development of novel therapies is critical for T-cell acute leukaemia (T-ALL). Here, we investigated the effect of inhibiting the MAPK/MEK/ERK pathway on T-ALL cell growth. Unexpectedly, MEK inhibitors (MEKi) enhanced growth of 70% of human T-ALL cell samples cultured on
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