R3030

Risperidone

≥98% (HPLC), powder, antipsychotic

• Synonyme(s) : R 64,766
• Formule empirique (notation de Hill): C₂₃H₂₇FN₄O₂
• Numéro CAS: 106266-06-2
• Poids moléculaire : 410.48
• Numéro MDL: MFCD00274576
• Code UNSPSC : 12352200
• ID de substance PubChem : 329824020
• Nomenclature NACRES : NA.77

Propriétés

• product name: Risperidone, ≥98% (HPLC), powder
• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to off-white
• Solubilité: DMSO: ≥5 mg/mL
• Auteur: Johnson & Johnson
• Température de stockage: room temp
• Chaîne SMILES: CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1
• InChI: 1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3
• Clé InChI: RAPZEAPATHNIPO-UHFFFAOYSA-N
• Informations sur le gène: human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

Description

Description générale

Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D₂, histamine H₁ and α₁ and α₂ adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autism.

Application

Risperidone has been used:

• to study its effects on bone formation and differentiation
• to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients
• to reverse induced schizophrenia-like behavior in mice

Actions biochimiques/physiologiques

Risperidone is an antipsychotic; serotonin-dopamine antagonist.

Caractéristiques et avantages

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges