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P6641

Sigma-Aldrich

1,2-Diacyl-sn-glycero-3-phospho-L-serine solution

≥97%, from bovine brain, chloroform:methanol solution

Synonyme(s) :

3-sn-Phosphatidyl-L-serine, L-α-Phosphatidyl-L-serine, PS, Phosphatidylserine

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About This Item

Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Source biologique

bovine brain

Niveau de qualité

200

Pureté

≥97%

Forme

chloroform:methanol solution

Groupe fonctionnel

phospholipid

Type de lipide

phosphoglycerides

Conditions d'expédition

dry ice

Température de stockage

−20°C

Application


  • Electrophoretic Light Scattering and Electrochemical Impedance Spectroscopy Studies of Lipid Bilayers Modified by Cinnamic Acid and Its Hydroxyl Derivatives.: This study explores the modification of lipid bilayers, specifically focusing on the interactions between cinnamic acid derivatives and lipid structures, including 1,2-Diacyl-sn-glycero-3-phospho-ʟ-serine solutions. It employs electrophoretic light scattering and electrochemical impedance spectroscopy to elucidate the electrochemical properties and stability of these modified bilayers, highlighting their potential in biophysical and biochemical applications (Naumowicz et al., 2020).

  • Silica-based Monolithic Capillary Columns Modified by Liposomes for Characterization of Analyte-Liposome Interactions by Capillary Liquid Chromatography.: This research investigates the use of silica-based monolithic capillary columns modified with liposomes, including 1,2-Diacyl-sn-glycero-3-phospho-ʟ-serine, to study analyte-liposome interactions. The capillary liquid chromatography technique used in this study provides insights into the behavior of analytes within lipid environments, which is crucial for understanding membrane interactions and developing lipid-based delivery systems (Moravcová et al., 2013).

Actions biochimiques/physiologiques

A slowly metabolized structural phospholipid found mainly in gray matter.

Attention

Solutions exposed to room temperature will decompose about 0.5% per day.

Remarque sur l'analyse

Actual concentration given on label.

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3

Organes cibles

Eyes,Central nervous system, Liver,Kidney, Respiratory system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

80.1 °F - closed cup

Point d'éclair (°C)

26.7 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificats d'analyse (COA)

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Riccardo Provenzani et al.
PloS one, 13(4), e0195668-e0195668 (2018-04-12)
Protein kinase C (PKC) isoforms play a pivotal role in the regulation of numerous cellular functions, making them extensively studied and highly attractive drug targets. Utilizing the crystal structure of the PKCδ C1B domain, we have developed hydrophobic isophthalic acid
Kwang-jin Cho et al.
The Journal of biological chemistry, 287(52), 43573-43584 (2012-11-06)
Oncogenic mutant Ras is frequently expressed in human cancers, but no anti-Ras drugs have been developed. Since membrane association is essential for Ras biological activity, we developed a high content assay for inhibitors of Ras plasma membrane localization. We discovered
T I Lin et al.
Journal of virology, 75(8), 3647-3656 (2001-03-27)
The viral ion channel protein M2 supports the transit of influenza virus and its glycoproteins through acidic compartments of the cell. M2 conducts endosomal protons into the virion to initiate uncoating and, by equilibrating the pH at trans-Golgi membranes, preserves
Christine A McCary et al.
The Biochemical journal, 441(1), 189-198 (2011-09-22)
Vitamin E isoforms have opposing regulatory effects on leucocyte recruitment during inflammation. Furthermore, in vitro, vitamin E isoforms have opposing effects on leucocyte migration across endothelial cells by regulating VCAM (vascular cell-adhesion molecule)-1 activation of endothelial cell PKCα (protein kinase
Lise Sofie H Nissen-Meyer et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(17), 6565-6575 (2011-04-29)
Molecular mechanisms involved in the replenishment of the fast neurotransmitters glutamate and GABA are poorly understood. Glutamine sustains their generation. However, glutamine formation from the recycled transmitters is confined to glial processes and requires facilitators for its translocation across the
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