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P5874

Sigma-Aldrich

PTACH

≥98% (HPLC), solid

Synonyme(s) :

Cpd 51, S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate

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About This Item

Formule empirique (notation de Hill):
C20H26N2O2S2
Numéro CAS:
848354-66-5
Poids moléculaire :
390.56
Numéro MDL:
MFCD08705329
Code UNSPSC :
12352202
ID de substance PubChem :
24724582
Nomenclature NACRES :
NA.77

Pureté

≥98% (HPLC)

Forme

solid

Solubilité

DMSO: 26 mg/mL

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c2ccccc2

InChI

1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)

Clé InChI

MDYDGUOQFUQOGE-UHFFFAOYSA-N

Actions biochimiques/physiologiques

HDAC inhibitor; more potent than the majority of HDAC inhibitors except for SAHA (gold standard).

Caractéristiques et avantages

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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Minghui Wang et al.
Neuron, 109(2), 257-272 (2020-11-26)
To identify the molecular mechanisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics profiling of four cortical areas across 364 donors with varying cognitive and neuropathological phenotypes. Our analyses revealed thousands

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