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Merck
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Key Documents

P4083

Sigma-Aldrich

Penicillin − Streptomycin − Neomycin Solution Stabilized

liquid, suitable for cell culture, BioReagent

Synonyme(s) :

Pen-Strep-Neo

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About This Item

Code UNSPSC :
12352207
Nomenclature NACRES :
NA.76

product name

Penicillin − Streptomycin − Neomycin Solution Stabilized, formulated to contain ~5,000 units penicillin, 5 mg streptomycin and 10 mg neomycin/mL, 0.1 μm filtered, BioReagent, suitable for cell culture

Niveau de qualité

300

Stérilité

0.1 μm filtered

Gamme de produits

BioReagent

Forme

liquid

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, tested

Spectre d'activité de l'antibiotique

Gram-negative bacteria
Gram-positive bacteria

Mode d’action

cell wall synthesis | interferes
protein synthesis | interferes

Conditions d'expédition

dry ice

Température de stockage

−20°C

Application

Penicillin-Streptomycin-Neomycin Solution Stabilized has been used to immerse alginate scaffold for disinfection. It has also been used as a cell culture media supplement to control bacterial contamination.

Actions biochimiques/physiologiques

Mode of Action: This product acts in three ways. Penicillin inhibits bacterial cell wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding. Neomycin inhibits initiation and elongation during protein synthesis.

Composants

This product is formulated to contain 5,000 units penicillin, 5 mg streptomycin and 10 mg neomycin/mL and is solubilized.

Autres remarques

20ml,100ml
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H317,H334

Classification des risques

Resp. Sens. 1 - Skin Sens. 1

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Goro Tanifuji et al.
Scientific reports, 7(1), 11688-11688 (2017-09-17)
Endosymbiotic relationships between eukaryotic and prokaryotic cells are common in nature. Endosymbioses between two eukaryotes are also known; cyanobacterium-derived plastids have spread horizontally when one eukaryote assimilated another. A unique instance of a non-photosynthetic, eukaryotic endosymbiont involves members of the
Cartilage regeneration in SCID mice using a highly organized three-dimensional alginate scaffold
Wang CC, et al.
Biomaterials and Medical Tribology, 33(1), 120-127 (2012)
Rich-club organization in effective connectivity among cortical neurons
Nigam S, et al.
The Journal of Neuroscience, 36(3), 670-684 (2016)
Seweryn Mroczek et al.
Nature communications, 8(1), 619-619 (2017-09-22)
FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene expression.
Hsiou-Hsin Tsai et al.
International journal of molecular sciences, 20(16) (2019-08-21)
The culture environment plays an important role for stem cells' cultivation. Static or dynamic culture preserve differential potentials to affect human mesenchymal stem cells' (hMSCs) proliferation and differentiation. In this study, hMSCs were seeded on fiber disks and cultured in
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