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Key Documents

L8643

Sigma-Aldrich

Lipopolysaccharides from Pseudomonas aeruginosa 10

purified by gel-filtration chromatography

Synonyme(s) :

LPS

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About This Item

Numéro MDL:
MFCD00131520
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Source biologique

Pseudomonas aeruginosa (10)

Niveau de qualité

200

Forme

lyophilized powder

Produit purifié par

gel-filtration chromatography

Impuretés

<3% Protein (Lowry)

Couleur

white to faint yellow

Solubilité

water: 4.90-5.10 mg/mL, cloudy to hazy, colorless to faintly yellow

Température de stockage

2-8°C

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Application

Lipopolysaccharides from Pseudomonas aeruginosa 10 has been used as an inflammatory mediator in cells.
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Autres remarques

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Austin Boucher et al.
Journal of immunology (Baltimore, Md. : 1950), 206(3), 540-553 (2020-12-18)
Macrophages are critical for regulating inflammatory responses. Environmental signals polarize macrophages to either a proinflammatory (M1) state or an anti-inflammatory (M2) state. We observed that the microRNA (miRNA) cluster mirn23a, coding for miRs-23a, -27a, and -24-2, regulates mouse macrophage polarization.
Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice.
Bruscia EM
American Journal of Respiratory Cell and Molecular Biology, 40, 295-295 (2009)
Clara cells attenuate the inflammatory response through regulation of macrophage behavior.
Snyder JC
American Journal of Respiratory Cell and Molecular Biology, 42, 161-171 (2010)
Daniel Sanchez-Guzman et al.
Biomaterials, 217, 119308-119308 (2019-07-07)
Most of current influenza virus vaccines fail to develop a strong immunity at lung mucosae (site of viral entry) due to sub-optimal vaccination protocols (e.g. inactivated virus administered by parenteral injections). Mucosal immunity could be improved by using locally-delivered vaccines
Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha.
Russell JP
Infection and Immunity, 64, 1565-1565 (1996)
Afficher tous les articles scientifiques apparentés

Articles

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

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