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I5404

Sigma-Aldrich

IgG2, Kappa from human myeloma plasma

purified immunoglobulin, >95% (SDS-PAGE)

Synonyme(s) :

Human IgG2-κ

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

human

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

purified immunoglobulin

Pureté

>95% (SDS-PAGE)

Conditions d'expédition

dry ice

Température de stockage

−20°C

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Description générale

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.
Human myeloma IgG2, κ is purified from human plasma by fractionation, ion-exchange and affinity chromatography procedures.

Application

The purified IgG2, κ may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays. Human myeloma IgG2, κa was used to characterize the trisulfide modifications in human and mouse antibodies and in flow cytometry.

Forme physique

Solution in 0.02 M Tris buffered saline, pH 8.0.

Remarque sur l'analyse

Identity is determined by immunoelectrophoresis and indirect ELISA.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Analytical biochemistry, 400(1), 89-98 (2010-01-21)
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