I4777
Interferon-γ from mouse
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonyme(s) :
IFN-γ
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About This Item
Produits recommandés
Source biologique
mouse
Niveau de qualité
Produit recombinant
expressed in E. coli
Pureté
≥98% (SDS-PAGE)
Forme
lyophilized powder
Poids mol.
protein 15.6 kDa
Conditionnement
pkg of 0.1 mg
Technique(s)
cell culture | mammalian: suitable
Impuretés
endotoxin, tested
Couleur
white
Solubilité
water: soluble 1.000 mL, clear, colorless
Numéro d'accès UniProt
Température de stockage
−20°C
Informations sur le gène
mouse ... Ifng(15978)
Application
Interferon-γ from mouse has been used:
- for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c+ (CD11 antigen-like family member C) lung macrophages
- for stimulation of murine macrophages to induce the production of nitrite and nitrate
- to check CCAAT/enhancer binding protein β (C/EBPβ)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation
Actions biochimiques/physiologiques
Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.
Forme physique
Lyophilized from a 0.2 μm filtered buffered solution. Package size based on protein content.
Remarque sur l'analyse
The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells.
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
Certificats d'analyse (COA)
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The eicosanoid prostaglandin E2 (PGE2 ) plays important roles in neuroinflammation and it is produced by the sequential action of the enzymes cyclooxygenase-2 (COX-2) and prostaglandin E synthase (PTGES). The expression of both enzymes and the production of PGE2 are
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