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Merck
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Key Documents

GHS1128

Sigma-Aldrich

Hematoxylin Solution, Gill No. 1

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About This Item

Numéro MDL:
Code UNSPSC :
41116124
ID de substance PubChem :
Nomenclature NACRES :
NA.47

Forme

solution

Niveau de qualité

Durée de conservation

Expiry date on the label.

IVD

for in vitro diagnostic use

Concentration

2 g/L

pH

2.5-3.5

Application(s)

hematology
histology

Température de stockage

room temp

Chaîne SMILES 

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

Clé InChI

WZUVPPKBWHMQCE-XJKSGUPXSA-N

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Application

Gill No. 1 formulation is used as a progressive cytology stain. Used with hematoxylin and eosin staining.

Autres remarques

2 g/L certified hematoxylin

Pictogrammes

Health hazardExclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - STOT RE 2 Oral

Organes cibles

Kidney

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Michael J Turner et al.
Journal of neuroimmunology, 285, 4-12 (2015-07-23)
Alemtuzumab, a monoclonal antibody directed against human CD52, is used in the treatment of MS. To characterize the impact of anti-CD52 administration, a monoclonal antibody to mouse CD52 (anti-muCD52) was generated and evaluated in EAE mouse models of MS. A
Eleni Maniati et al.
Cell reports, 30(2), 525-540 (2020-01-16)
Although there are many prospective targets in the tumor microenvironment (TME) of high-grade serous ovarian cancer (HGSOC), pre-clinical testing is challenging, especially as there is limited information on the murine TME. Here, we characterize the TME of six orthotopic, transplantable syngeneic
Li-Gen Lin et al.
Journal of medicinal chemistry, 51(15), 4419-4429 (2008-07-10)
Protein tyrosine kinase (PTK) inhibitors represent emerging therapeutics for cancer chemoprevention. In our study, hematoxylin (26) was identified as one of the most remarkable c-Src inhibitors in an orthogonal compound-mixing library (32200 compounds) by using an ELISA-based automated high-throughput screening
Hideki Ishii et al.
Bioorganic & medicinal chemistry letters, 22(3), 1469-1474 (2012-01-17)
SAR studies for the exploration a novel class of anti-human immunodeficiency virus type 1 (HIV-1) agents based on the hematoxylin structure (1) are described. The systematic deoxygenations of 1 including asymmetric synthesis were conducted to obtain a compound showing high
Devalingam Mahalingam et al.
Autophagy, 10(8), 1403-1414 (2014-07-06)
We previously reported that inhibition of autophagy significantly augmented the anticancer activity of the histone deacetylase (HDAC) inhibitor vorinostat (VOR) through a cathepsin D-mediated mechanism. We thus conducted a first-in-human study to investigate the safety, preliminary efficacy, pharmacokinetics (PK), and

Contenu apparenté

Brève information sur le domaine de la cytologie, son rôle dans le cytodiagnostic et l'utilisation de colorants standards et spéciaux pour l'analyse au microscope afin de détecter des anomalies cellulaires.

Brief information on the field of cytology, its role in cytodiagnosis and the use of standard and special stains for microscopic analysis to detect cellular abnormalities.

Brief information on the field of cytology, its role in cytodiagnosis and the use of standard and special stains for microscopic analysis to detect cellular abnormalities.

Brief information on the field of cytology, its role in cytodiagnosis and the use of standard and special stains for microscopic analysis to detect cellular abnormalities.

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