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G8541

Sigma-Aldrich

Ala-Gln

200 mM, solution, sterile-filtered, Biotechnology Performance Certified

Synonyme(s) :

Alanyl-glutamine, Glutamine-S

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About This Item

Formule empirique (notation de Hill):
C8H15N3O4
Numéro CAS:
39537-23-0
Poids moléculaire :
217.22
Numéro MDL:
MFCD00133046
Code UNSPSC :
12352209
ID de substance PubChem :
24895343
Nomenclature NACRES :
NA.75

Qualité

Biotechnology Performance Certified

Niveau de qualité

400

Stérilité

sterile-filtered

Forme

solution

Concentration

200 mM

Impuretés

endotoxin, tested

Température de stockage

2-8°C

Chaîne SMILES 

NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O

InChI

1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1

Clé InChI

HJCMDXDYPOUFDY-WHFBIAKZSA-N

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Description générale

Ala-Gln supplement provides a stable form of L-glutamine while in solution.

Application

Ala-Gln has been used as a supplement in Dulbecco′s Modified Eagle Medium (DMEM) media-rich in glucose and pyruvate to culture luciferase-expressing MDA-MB-231-luc tumor cells to measure the bioluminescence signals of cells leaking during intra-bone marrow transplantation (IBMT) from dissected long bones. It has also been used as a DMEM - high glucose media to culture human cell lines.

Autres remarques

Contains the dipeptide L-Alanyl-L-glutamine. 200 mM supplied in 0.85% NaCl.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Dieter Fink et al.
PloS one, 14(11), e0224576-e0224576 (2019-11-08)
Intra-bone marrow transplantation (IBMT) has been adapted for mouse models to improve the seeding efficiency of transplanted hematopoietic stem and progenitor cells. Commonly used injection volumes for IBMT into the tibia differ between 10 and 40 μL even though considerable
Daren K Heyland et al.
JPEN. Journal of parenteral and enteral nutrition, 39(4), 401-409 (2014-05-08)
The recent large randomized controlled trial of glutamine and antioxidant supplementation suggested that high-dose glutamine is associated with increased mortality in critically ill patients with multiorgan failure. The objectives of the present analyses were to reevaluate the effect of supplementation
Marek Bartosovic et al.
Nature biotechnology, 39(7), 825-835 (2021-04-14)
In contrast to single-cell approaches for measuring gene expression and DNA accessibility, single-cell methods for analyzing histone modifications are limited by low sensitivity and throughput. Here, we combine the CUT&Tag technology, developed to measure bulk histone modifications, with droplet-based single-cell
Bente K Hansen et al.
Structure (London, England : 1993), 28(5), 528-539 (2020-03-30)
Phenomycin is a bacterial mini-protein of 89 amino acids discovered more than 50 years ago with toxicity in the nanomolar regime toward mammalian cells. The protein inhibits the function of the eukaryotic ribosome in cell-free systems and appears to target translation
Hiroshi Ono et al.
Cancer medicine, 3(3), 632-642 (2014-03-05)
Small-cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis. To identify accurate predictive biomarkers and effective therapeutic modalities, we focus on a long noncoding RNA, Hox transcript antisense intergenic RNA (HOTAIR), and investigated its expression, cellular
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L-Glutamine in Cell Culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

L-Glutamine in Cell Culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

L-Glutamine in Cell Culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

L-Glutamine in Cell Culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

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