G0516
α2-hs-Glycoprotein from human plasma
≥90% (SDS-PAGE), lyophilized powder
Synonyme(s) :
Plasma glycoprotein
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About This Item
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Catégories apparentées
Description générale
α2-HS glycoprotein (A2HS) is a glycoprotein (molecular weight 49,000) present in human plasma at levels ranging between 40 and 85 mg/dl. A2HS is a major protein component of the bone matrix and could be involved both in mineralization and bone resorption.
Application
Fetuin (α2-HS-glycoprotein) was used to confirm its role in enhancing the suppression of tumor necrosis factor (TNF) release from activated macrophages by CNI-1493. It was also used in 2-dimensional electrophoresis to detect glycosylation and influence spot pattern.
Conditionnement
Package size based on protein content
Forme physique
Lyophilized from 20 mM Tris-HCl, pH 8.0, with 200 mM NaCl
Clause de non-responsabilité
Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d′importation et d′exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L′acheteur (c′est-à-dire l′utilisateur FINAL) est tenu d′obtenir une autorisation d′importation auprès du ministère français de la recherche, mentionné à l′article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l′autorisation d′importation requise.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Les clients ont également consulté
The Journal of clinical investigation, 64(4), 1118-1129 (1979-10-01)
A nonspecific opsonin function has been ascribed to human alpha 2 HS glycoprotein. Its serum level has been shown to be decreased in trauma patients. Recent studies from this laboratory revealed a heterogeneity among the products obtained in the course
Methods in molecular biology (Clifton, N.J.), 446, 199-214 (2008-04-01)
The detailed characterization of complex protein mixtures as in samples from biological sources cannot be sufficiently performed by separation of polypeptides according to their molecular weight as is done by conventional sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) (1DE). For analysis
American journal of human genetics, 37(6), 1098-1105 (1985-11-01)
The genetic polymorphism of human alpha 2-HS glycoprotein was studied by ultrathin-layer isoelectric focusing in a pH range 4.2-4.9 followed by immunoblotting using antisera specific for the protein. Three common phenotypes, HSGA1-1, HSGA2-2, and HSGA1-2, were easily recognized using this
Proceedings of the National Academy of Sciences of the United States of America, 95(24), 14429-14434 (1998-11-25)
Macrophages become activated by bacterial endotoxin (lipopolysaccharide) and other stimuli to release proinflammatory cytokines and NO. To prevent release of toxic or potentially lethal quantities of these factors, the state of macrophage activation is counter-regulated by anti-inflammatory mediators (e.g., glucocorticoid
Nanoscale, 11(8), 3665-3673 (2019-02-12)
The study of protein interactions with gold nanoparticles (GNP) is a key step prior to any biomedical application. These interactions depend on many GNP parameters such as size, surface charge, chemistry, and shape. In this work, we propose to use
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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