F8053

Anti-FADD antibody, Mouse monoclonal

clone FD19, purified from hybridoma cell culture

• Synonyme(s) : Anti-Fas Associated Death Domain
• Numéro MDL: MFCD01633337
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: FD19, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~28 kDa
• Espèces réactives: human
• Concentration: ~2 mg/mL
• Technique(s): immunoprecipitation (IP): suitable; indirect ELISA: suitable; microarray: suitable; western blot: 0.5-1 μg/mL using total cell extracts of A431 cells
• Isotype: IgG1
• Numéro d'accès UniProt: Q13158
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... FADD(8772)

Description

Description générale

Anti-FADD antibody, Mouse monoclonal (mouse IgG1) is derived from the FD19 hybridoma produced by the fusion of murine myeloma cells (NS1) and splenocytes from mouse immunized with purified recombinant human FADD.

Immunogène

purified recombinant human FADD.

Application

Anti-FADD antibody, Mouse monoclonal has been used in:

• immunoblotting
• immunoprecipitation
• enzyme-linked immunosorbent assay (ELISA)

Actions biochimiques/physiologiques

FADD (Fas Associated Death Domain) is associated with various non-apoptotic cellular pathways such as regulation of cell cycle machinery in T lymphocytes connected to the phosphorylation state of FADD and to the FasL/TRAIL-induced transcriptional activation of c-fos protooncogene. It also interacts with the hepatitis C virus core protein in the HEK-293 cell line.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)