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Key Documents

E1625

Sigma-Aldrich

Elastin from bovine neck ligament

powder

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About This Item

Numéro CAS:
9007-58-3
Numéro CE :
232-701-4
Numéro MDL:
MFCD00130999
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61

Source biologique

bovine neck ligament

Niveau de qualité

200

Forme

powder

Numéro d'accès UniProt

P04985

Température de stockage

2-8°C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

Clé InChI

DPUYCSDGMSDKKV-MKBYFEBXSA-N

Informations sur le gène

cow ... ELN(280781)

Application

Elastin is a structural protein which has been used in studies of Chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Highly stable and hemocompatible protein now finding use in construction of biomaterials as a result of several strategies for its solubilization.

Actions biochimiques/physiologiques

Protein responsible for the elasticity of many tissues. It is especially important in blood vessels, where it comprises about 50% of the dry tissue weight.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

H M Morrison et al.
Biochimica et biophysica acta, 1430(2), 179-190 (1999-03-20)
Solubilization of elastin by human leukocyte elastase (HLE) cannot be analyzed by conventional kinetic methods because the biologically relevant substrate is insoluble and the concentration of enzyme-substrate complex has no physical meaning. We now report quantitative measurements of the binding
N Vyavahare et al.
The American journal of pathology, 155(3), 973-982 (1999-09-17)
Elastin, an abundant structural protein present in the arterial wall, is prone to calcification in a number of disease processes including porcine bioprosthetic heart valve calcification and atherosclerosis. The mechanisms of elastin calcification are not completely elucidated. In the present
Katsuhiko Tsuchida et al.
Scientific reports, 10(1), 21667-21667 (2020-12-12)
Oxidative stress is associated with photoaging of the skin as well as with skin cancer, and is therefore, critical to monitor. Ultraweak photon emission (UPE) is extremely weak light generated during the oxidative process in the living body and has
Isabella C P Rodrigues et al.
Artificial organs, 45(5), E113-E122 (2020-11-11)
Tubular polymer scaffolds based on tissue engineering techniques have been studied as potential alternatives for vascular regeneration implants. The blood vessels of the cardiovascular system are mainly fibrous, composed of collagen (Col) and elastin (El), and its inner layer consists
Yueying Zhu et al.
Virulence, 13(1), 1221-1241 (2022-07-27)
Bacterial pathogens have a critical impact on aquaculture, a sector that accounts for half of the human fish consumption. Flavobacterium psychrophilum (phylum Bacteroidetes) is responsible for bacterial cold-water disease in salmonids worldwide. The molecular factors involved in host invasion, colonization
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