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Merck
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Key Documents

C4361

Sigma-Aldrich

Bovine Collagen Type I

from bovine skin, liquid, 1 mg/mL, FITC Conjugated, used for gel analysis, cell seeding, and collagenase assays

Synonyme(s) :

Collagen from bovine skin

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About This Item

Numéro CAS:
308064-12-2
Numéro MDL:
MFCD02264428
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.32

product name

Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution

Source biologique

bovine skin

Niveau de qualité

200

Forme

solution

Concentration

~1 mg/mL

Numéro d'accès UniProt

P02453
P02465
P03956
P81563
Q9EPL5

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

cow ... COL1A1(282187) , COL1A2(282188)
human ... MMP1 (includes EG:4312)
mouse ... MMP1 (includes EG:4312)
rat ... MMP1 (includes EG:4312)

Description générale

Type I collagen is the major collagen of tendon and bone, but it is widely distributed in other tissues, such as skin, cornea, tooth dentin, heart valve, lung, liver, fascia and scar tissue.

Application

Collagen Type I-FITC Conjugate from bovine skin has been used in collagen I gel deformation analysis. It has also been used to coat silicone elastic membranes for seeding cells for various experimental studies. It can also be used as a substrate for assaying mammalian collagenase activity in cell culture.

Actions biochimiques/physiologiques

Collagen type I offers mechanical stability, strength and toughness to a range of tissues from tendons and ligaments, to skin, cornea, bone and dentin.

Forme physique

Supplied in 0.01 M acetic acid.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Faceshields, Gloves, Goggles

Certificats d'analyse (COA)

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Ayodele Olaolu Oladejo et al.
Journal of inflammation research, 15, 807-825 (2022-02-18)
Endometritis is a female reproductive disease that affects the cattle industries development and microRNAs (miRNAs) play a pivotal role and critical regulators of the innate immune response in varieties of diseases. The present study intends to investigate the regulatory role
F Nelson et al.
The Journal of clinical investigation, 102(12), 2115-2125 (1998-12-17)
There is evidence to suggest that the synthesis of type II collagen is increased in osteoarthritis (OA). Using an immunoassay, we show that the content of the C-propeptide of type II procollagen (CPII), released extracellularly from the newly synthesized molecule
Sjors Maassen et al.
Free radical biology & medicine, 188, 287-297 (2022-06-27)
5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is unclear. Here, we show by
Processing of collagen-based biomaterials and the resulting materials properties
Meyer M, et al.
BioMedical Engineering OnLine, 18 (2019)
Live free or die: Stretch-induced apoptosis occurs when adaptive reorientation of annulus fibrosus cells is restricted
Abbott RD, et al.
Biochemical and Biophysical Research Communications, 421(2), 361-366 (2012)
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