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Key Documents

C3527

Sigma-Aldrich

Anti-C-Reactive Protein antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

Synonyme(s) :

Anti-CRP

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About This Item

Numéro MDL:
MFCD00162183
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

rabbit

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

IgG fraction of antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

human

Conditionnement

vial of 2 mL lyophilized antiserum

Technique(s)

indirect ELISA: 1:10,000-1:20,000

Numéro d'accès UniProt

P02741

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CRP(1401)

Description générale

C-reactive protein (CRP) is an acute-phase pentraxin protein. It is synthesized by the liver. This gene is mapped to human chromosome 1q23. It has two exons and an intron. It is located within the complement membrane complex in early atherosclerotic tissue.

Application

Anti-C-Reactive Protein antibody produced in rabbit has been used in electro immunoassay, and enzyme-linked immunosorbent assay (ELISA).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)

Actions biochimiques/physiologiques

C-reactive protein (CRP) is considered as a major biomarker of sterile inflammation. It is mainly used to observe the treatment response which can predict long-term consequence in inflammatory diseases. CRP facilitates opsonization of low-density lipoprotein by macrophages.

Forme physique

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Reconstitution

Reconstitute with 2 ml deionized water.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

C-Reactive Protein Production in Term Human Placental Tissue
Malek A, et al.
Placenta, 27(6), 619-625 (2006)
Protein and amino acid metabolism in three-to twelve-month-old infants fed human milk or formulas with varying protein concentrations
AAkeson PMK, et al.
Journal of Pediatric Gastroenterology and Nutrition, 26(3), 297-304 (1998)
C-Reactive Protein Levels at the Midpregnancy Can Predict Gestational Complications
Vecchie A, et al.
BioMed Research International, 2018 (2018)
Relation of polymorphism within the C-reactive protein gene and plasma CRP levels
Suk HJ, et al.
Atherosclerosis, 178(1), 139-145 (2005)
Luigi Raio et al.
Journal of hypertension, 37(5), 1012-1017 (2019-03-19)
Angiogenic and inflammatory factors have been shown to play an important role in the pathogenesis of preeclampsia. However, there is little information on their interaction. The aims of this study were to investigate the longitudinal pattern of inflammatory markers, such
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