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B3383

Sigma-Aldrich

Benzidine dihydrochloride

≥99% (titration)

Synonyme(s) :

4,4′-Diaminobiphenyl dihydrochloride

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About This Item

Formule empirique (notation de Hill):
C12H12N2 · 2HCl
Numéro CAS:
531-85-1
Poids moléculaire :
257.16
Numéro Beilstein :
3914846
Numéro CE :
208-519-6
Numéro MDL:
MFCD00040389
Code UNSPSC :
12352116
ID de substance PubChem :
24891713
Nomenclature NACRES :
NA.25

Niveau de qualité

200

Pureté

≥99% (titration)

Forme

powder

Chaîne SMILES 

Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

Clé InChI

RUAXWVDEYJEWRY-UHFFFAOYSA-N

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Application

Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.

Actions biochimiques/physiologiques

Tumor initiator in mammary glands of experimental animal.

Avertissement

Cancer suspect agent.

Pictogrammes

Health hazardExclamation markEnvironment
GHS08,GHS07,GHS09

Mention d'avertissement

Danger

Mentions de danger

H302,H350,H410

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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K C Morton et al.
Carcinogenesis, 2(8), 747-752 (1981-01-01)
To evaluate the role of metabolism in benzidine (BZ) carcinogenesis, BZ and 2 or its metabolites, N,N'-diacetylbenzidine and N-hydroxy-N,N'-diacetylbenzidine (NOHDABZ), were given by i.p. injection to female CD rats twice weekly for 4 weeks beginning at 30 days of age.
Jungsun Park et al.
American journal of industrial medicine, 52(8), 625-632 (2009-06-30)
Many corporations move their manufacturing facilities or technologies from developed to developing countries. Stringent regulations have made it costly for industries to operate in developed, industrialized countries. In addition, labor costs are high in these countries, and there is increasing
Jung Woo Lee et al.
Chemical communications (Cambridge, England), 48(3), 422-424 (2011-11-15)
We report a facile route to synthesize size tunable Fe(3)O(4) nanoparticles (NPs)-carbon nitride nanotube (CNNT) hybrids. These hybrids showing the water-soluble property are proven to exhibit ultra high peroxidase mimetic activity compared to those of pure NPs, where a colorless
Juliana Piva de Almeida et al.
Forensic science international, 206(1-3), 58-61 (2010-07-21)
Bloodstains often constitute the major physical evidence in crime investigation. Diluted blood invisible to the naked eye can be detected through presumptive tests however such tests can damage samples and prevent further processing such as DNA analysis. In this study
Bhim Bali Prasad et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 912, 65-74 (2012-12-25)
An alternative method is presented for the modification of pencil graphite fibers using surface imprinting technology. In this new approach, we have adopted surface initiated electropolymerization of benzidine monomer, with simultaneous imprinting of template (d- and l-methionine), on carboxylated multiwalled
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