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Merck
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Key Documents

A6582

Sigma-Aldrich

Antifoam A concentrate

active silicone polymer 100%

Synonyme(s) :

Antifoam agent, Antifoam solution, Foam control agent

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About This Item

Code UNSPSC :
12161901
Nomenclature NACRES :
NA.85

Niveau de qualité

Forme

emulsion (aqueous)

Technique(s)

cell culture | hybridoma: suitable
microbiological culture: suitable

Densité

0.97 g/mL at 25 °C

Application(s)

microbiology

Température de stockage

room temp

Adéquation

(Mammalian (suspension))
bacteria (fermentation)

Description générale

Antifoam A is a silicone-based product used to prevent or minimize foaming in both microbial fermentation systems and mammalian suspension cultures. Control of foaming minimizes damage to the cells, resulting in increased protein/antibody production. Extremely effective for aqueous and non-aqueous systems. Effective at concentrations in the 1-50ppm range.

Application

Antifoam A concentrate has been used:
  • in bioreactor culture for Staphylococcal enterotoxin C (SEC) production.
  • to prevent foam formation during the aerobic treatment of sludge.
  • to study the impact of surface tension on bioaerosol generation during bubbling.

Caractéristiques et avantages

  • Molecular biology grade and tested for use in bacterial fermentation.
  • Extremely effective foam suppressor for aqueous and non-aqueous systems.
  • Made of 100% active silicone polymer, free of emulsifiers.
  • Typically, effective at 1-100 ppm.
  • Product will be stable in the pH range of 5 to 9.
  • Can be directly added to a fermentation medium but it is not recommended that it be pumped to a fermenter on an as-needed basis.

Composants

Antifoam A is a 100% active silicon polymer containing no non-ionic emulsifiers .

Notes préparatoires

Antifoam A can be pre-diluted with 3-10 parts of aqueous propylene glycol or non-aqueous vegetable oil with slow mixing.

Produit(s) apparenté(s)

Pictogrammes

Environment

Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

>213.8 °F - closed cup

Point d'éclair (°C)

> 101 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Experience with a perfo-suction system for the recovery of schistosomes from laboratory rodents
T. F. H. G. Jackson, C. D. Dettman, et al.
Laboratory Animal Science, 16, 65-67 (1982)
The biodegradability of aquatic worm predated waste activated sludge: A sequential aerobic and anaerobic treatment approach
de Valk S, et al.
bioresource technology reports, 12.0, 100606-100606 (2020)
Bioaerosol Release from Concentrated Microbial Suspensions in Bubbling Processes
Kruglyakova E, et al.
Air quality, atmosphere, & health, 13.0, 2029-2029 (2022)
Factors affecting staphylococcal enterotoxin C bovine production in milk
Hunt K, et al.
International dairy journal, 39(1), 41-46 (2014)
F P Ernani et al.
Infection and immunity, 61(6), 2596-2601 (1993-06-01)
Substantial evidence indicates that molecules released by infectious organisms affect virulence and influence immunity to infection. The characterization of extracellular molecules and their mechanism of release is therefore critical to understanding host-parasite relationships. The cestode parasite Mesocestoides corti is known

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