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Key Documents

A3313

Sigma-Aldrich

Anti-Human Polyvalent Immunoglobulins (α, γ and μ-chain specific)−Alkaline Phosphatase antibody produced in goat

affinity isolated antibody, buffered aqueous glycerol solution

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Niveau de qualité

Conjugué

alkaline phosphatase conjugate

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

buffered aqueous glycerol solution

Espèces réactives

human

Technique(s)

direct ELISA: 1:30,000
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50
western blot: 1:30,000

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

Human immunoglobulins are glycoproteins that regulate immune responses to infections and allergies. Anti-human polyvalent immunoglobulins can be used for serological analyses in diseased population groups. These antibodies may also be used for studying xenotransplantation models and immunological disorders such as rheumatoid arthritis. Anti-Human Polyvalent Immunoglobulins (α, γ and μ-chain specific)-Alkaline Phosphatase antibody is specific for human IgG, IgA and IgM when tested against human IgA, IgG, IgM, Bence Jones κ, and λ myeloma proteins.

Immunogène

Purified human IgG, IgA and IgM

Application

Anti-Human Polyvalent Immunoglobulins (α, γ and μ-chain specific)-Alkaline Phosphatase antibody is suitable for use in western blot and immunostaining techniques.
The presence of IgG was detected in normal human sera using alkaline phosphatase-conjugated goat anti-human polyvalent IgG (chain specific) by ELISA at a concentration of 1:1000. An ELISA assay was performed using alkaline phosphatase-conjugated goat anti-human IgG polyvalent antibody to detect natural antibodies to KLH in human sera.

Forme physique

Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 10 mM glycine, 1 mM MgCl2, 50% glycerol and 15 mM sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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John S Spencer et al.
Clinical and vaccine immunology : CVI, 18(2), 260-267 (2010-12-24)
A simple serodiagnostic test based on the Mycobacterium leprae-specific phenolic glycolipid I(PGL-I), for individuals with leprosy is nearly universally positive in leprosy patients with high bacillary loads but cannot be used as a stand-alone diagnostic test for the entire spectrum
Angela Barone et al.
The Journal of biological chemistry, 288(14), 10035-10050 (2013-02-14)
Due to their pluripotency and growth capability, there are great expectations for human embryonic stem cells, both as a resource for functional studies of early human development and as a renewable source of cells for use in regenerative medicine and
Luisa Fernanda Duarte et al.
Colombia medica (Cali, Colombia), 45(2), 61-66 (2014-08-08)
To compare the diagnostic performance of seven methods to determine Trypanosoma cruzi infection in patients with chronic Chagas disease. Analytical study, using the case-control design, which included 205 people (patients with Chagasic cardiomyopathy, n=100; control group, n=105). Three enzyme linked
S A Pesoa et al.
Autoimmunity, 4(3), 171-179 (1989-01-01)
The distribution of frequencies of HLA-DR alloantigens in HLA-DR4 negative subjects was determined in patients with Rheumatoid arthritis (RA) and normal individuals. An increased incidence of HLA-DR1 alloantigen in DR4 negative RA patients (45.9%) compared with DR4 negative healthy controls
Béatrice Volney et al.
Acta tropica, 82(1), 11-23 (2002-03-21)
This paper describes a sero-epidemiological study of malaria prevalence in French Guiana. An immunofluorescence assay and an enzyme-linked immunosorbent assay were used to detect antibodies against blood-stage antigens and synthetic peptides mimicking the repetitive epitope of the sporozoites of Plasmodium

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