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A273

Sigma-Aldrich

Monoclonal Anti-Na+/K+ ATPase (α3 Subunit) antibody produced in mouse

1 mg/mL, clone XVIF9-G10, ascites fluid

Synonyme(s) :

Anti-AHC2, Anti-ATP1A1, Anti-CAPOS, Anti-DEE99, Anti-DYT12, Anti-RDP

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About This Item

Numéro MDL:
MFCD01322380
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

XVIF9-G10, monoclonal

Poids mol.

antigen ~110 kDa

Espèces réactives

human, rat, monkey, sheep, rabbit, guinea pig, canine

Concentration

1 mg/mL

Technique(s)

immunohistochemistry (frozen sections): 3 μg
western blot: 1 μg

Isotype

IgG1

Numéro d'accès UniProt

P13637

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ATP1A3(478)
rat ... Atp1a3(24213)

Description générale

Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody reacts specifically with Na+/K+ ATPase α3 subunit. By immunoblotting, the product reacts with human, monkey, sheep, canine, rabbit, guinea pig and rat tissues in which the α3 subunit is expressed. Immunohistochemical staining is consistent with the plasma membrane localization of Na+/K+ ATPase.
Na+/K+ transporting ATPase subunit α1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.

Immunogène

canine cardiac microsomes.

Application

Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody has been used for chemiluminescent western blot analysis. The product has also been used for co-immunoprecipitation applications.

Forme physique

Solution in phosphate buffered saline containing 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Emmanuelle Berret et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(7), 3067-3078 (2013-02-15)
The median preoptic nucleus (MnPO) holds a strategic position in the hypothalamus. It is adjacent to the third ventricle; hence, it can directly access the ionic composition of the CSF. MnPO neurons play a critical role in hydromineral homeostasis regulation
K Pather et al.
Thrombosis research, 177, 51-58 (2019-03-10)
Platelet-tumour cell interaction is implicated in the initiation of breast cancer-associated thrombosis, with hormone-therapy (Tamoxifen/Anastrozole), increasing this risk. However, recent in vitro research indicates that Tamoxifen inhibits platelet activation, while the effects of Anastrozole on platelet activation are not well
Athina Zouzoulas et al.
The Journal of biological chemistry, 281(13), 8539-8544 (2006-02-01)
The gamma modulator (FXYD 2) is a member of the FXYD family of single transmembrane proteins that modulate the kinetic behavior of Na,K-ATPase. This study concerns the identification of regions in the alpha subunit that are important for its functional
Steven J Clapcote et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(33), 14085-14090 (2009-08-12)
In a mouse mutagenesis screen, we isolated a mutant, Myshkin (Myk), with autosomal dominant complex partial and secondarily generalized seizures, a greatly reduced threshold for hippocampal seizures in vitro, posttetanic hyperexcitability of the CA3-CA1 hippocampal pathway, and neuronal degeneration in
Paola Vagni et al.
Nature communications, 13(1), 3678-3678 (2022-06-28)
Retinal prostheses hold the potential for artificial vision in blind people affected by incurable diseases of the outer retinal layer. Available technologies provide only a small field of view: a significant limitation for totally blind people. To overcome this problem

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