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Merck
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Key Documents

A1900

Sigma-Aldrich

Albumin, Monomer bovine

Monomer ≥97 %

Synonyme(s) :

Albumin powder, Bovine albumins

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About This Item

Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
eCl@ss :
42010201
Nomenclature NACRES :
NA.26

Source biologique

bovine

Niveau de qualité

Pureté

≥97% (PAGE)

Forme

lyophilized powder

Composition

Monomer, ≥97%

Solubilité

H2O: soluble 50 mg/mL

Numéro d'accès UniProt

Température de stockage

2-8°C

Informations sur le gène

bovine ... ALB(280717)

Description générale

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

Application

Albumin, Monomer bovine has been used as a:
  • molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops
  • standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration
  • model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies

The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.

Actions biochimiques/physiologiques

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.

Notes préparatoires

Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Piramon Hampitak et al.
ACS sensors, 5(11), 3520-3532 (2020-10-27)
We present a sensitive and low-cost immunoassay, based on a customized open-source quartz crystal microbalance coupled with graphene biointerface sensors (G-QCM), to quantify antibodies in undiluted patient serum. We demonstrate its efficacy for a specific antibody against the phospholipase A2
Mingshan Li et al.
Protein science : a publication of the Protein Society, 29(2), 443-454 (2019-10-28)
Methylation of specific chemoreceptor glutamyl residues by methyltransferase CheR mediates sensory adaptation and gradient sensing in bacterial chemotaxis. Enzyme action is a function of chemoreceptor signaling conformation: kinase-off receptors are more readily methylated than kinase-on, a feature central to adaptational
Yu Isakari et al.
Biotechnology journal, 13(7), e1700738-e1700738 (2018-02-03)
Combining chemical reaction with separation offers several advantages. In this work possibility to induce spontaneous desorption of adsorbed macromolecules, once being PEGylated, through adjustment of the reagent composition is investigated. Bovine serum albumin (BSA) and activated oligonucleotide, 9T, are used
Secondary structural change of bovine serum albumin in thermal denaturation up to 130 degrees C and protective effect of sodium dodecyl sulfate on the change.
Moriyama, Y., et al.
The Journal of Physical Chemistry B, 112, 16585-16589 (2008)
Pasquale Aragona et al.
Translational vision science & technology, 8(6), 2-2 (2019-11-07)
To assess the physicochemical properties of hyaluronic acid (HA)-based artificial tears. The average molecular weight (MW) and polydispersion index (PDI) of HA in 18 commercially available artificial tears were determined by light scattering/high-performance liquid chromatography. Osmolality, pH, viscosity, and sodium

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