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Key Documents

94258

Sigma-Aldrich

Eriodictyol

≥95.0% (HPLC)

Synonyme(s) :

3′,4′,5,7-Tetrahydroxyflavanone

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About This Item

Formule empirique (notation de Hill):
C15H12O6
Numéro CAS:
Poids moléculaire :
288.25
Numéro MDL:
Code UNSPSC :
12352205
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Niveau de qualité

Pureté

≥95.0% (HPLC)

Forme

powder

Application(s)

metabolomics
vitamins, nutraceuticals, and natural products

Température de stockage

−20°C

Chaîne SMILES 

O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)C1

InChI

1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2

Clé InChI

SBHXYTNGIZCORC-UHFFFAOYSA-N

Description générale

Eriodictyolis a bitter-masking dietary flavonoid primarily extracted from yerba Santa Clause (Eriodictyon californicum) and Dracocephalum rupestre, but also present in many other citrus fruits, medicinal plants, and vegetables.

Application

Eriodictyolmay has been used to study its mechanism on IgE/Ag-induced type I hypersensitivity inhibition at the level of mast cell degranulation and ceramide kinase activity. It may also be used to understand its potential antidiabetic activity and its neuroprotective activity via activation of the Nrf2/ARE signaling pathway.

Actions biochimiques/physiologiques

Eriodictyolis absorbed in the body slowly and can be found in plasma and urine as homoeriodictyol, a conjugated form. It has many pharmacological properties such as antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, anti-obesity, neuroprotective, cardioprotective, and hepatoprotective.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

For this product we use the non-stereospecific CAS number. It is expected that the natural enantiomer is predominant, however the substance is prone to racemization in solution. The product is therefore not specified stereospecifically and is only recommended to be used for non-stereospecific analysis.

Code de la classe de stockage

11 - Combustible Solids

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Behavioural brain research, 312, 321-332 (2016-06-30)
Cerebral ischemia is a common disease and one of the most common causes of death and disability worldwide. The lack of glucose and oxygen in neuronal tissue leads to a series of inflammatory events, culminating in neuronal death. Eriodictyol is
Zirong Deng et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 6681352-6681352 (2021-01-09)
Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is
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Archives of pharmacal research, 43(6), 582-592 (2020-07-01)
Eriodictyol is a flavonoid in the flavanones subclass. It is abundantly present in a wide range of medicinal plants, citrus fruits, and vegetables that are considered to have potential health importance. Having the considerable medicinal properties, eriodictyol has been predicted
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Journal of natural products, 74(5), 1061-1065 (2011-04-21)
Three new benzodihydrofurans (1-3) and seven known aromatic compounds (4-10) were isolated from the roots of Cyperus teneriffae. Vibrational circular dichroism spectroscopy was used to define the absolute configuration of 1.
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Natural product communications, 7(4), 471-474 (2012-05-12)
MeOH extracts of 37 herbs were tested in screening experiments for rat intestinal alpha-glucosidase. The MeOH extract of the aerial parts of Scutellaria lateriflora L. (Lamiaceae) significantly inhibited sucrase and maltase activities, using sucrose and maltase as the substrates. Enzyme

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