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Key Documents

57600

Sigma-Aldrich

IL-2 human

≥98% (GE), recombinant, expressed in E. coli, liquid

Synonyme(s) :

IL-2, TCGF, hIL-2

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.32

product name

Interleukin-2 human, recombinant, expressed in E. coli, ~10000 U/mL

Source biologique

human

Niveau de qualité

Produit recombinant

expressed in E. coli

Forme

liquid

Poids mol.

Mr ~15500

Conditionnement

vial of 1 mL

Concentration

~10000 U/mL

Couleur

colorless

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−70°C

Informations sur le gène

human ... IL2(3558)

Actions biochimiques/physiologiques

Promotes the growth of IL-2 dependent lymphocytes. Amino acid sequence of IL-2.

Conditionnement

One vial contains 10′000 Units

Attention

Stable at −20 °C; prepare appropriate aliquots and avoid repeated freezing and thawing, since aggregation may occur resulting in apparent loss of activity.

Définition de l'unité

1 U corresponds to the unit activity in the colorimetric MTT-assay with CTLL-2 cells.

Forme physique

Clear; colorless solution in Dulbecco-PBS; containing 1 mg BSA/mL.

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various
Cecilie Brekke Rygh et al.
PloS one, 9(9), e108414-e108414 (2014-10-01)
There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for glioblastoma targeting NG2/CSPG4 with mAb9.2.27
Nabil Ahmed et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(15), 1688-1696 (2015-03-25)
The outcome for patients with metastatic or recurrent sarcoma remains poor. Adoptive therapy with tumor-directed T cells is an attractive therapeutic option but has never been evaluated in sarcoma. We conducted a phase I/II clinical study in which patients with

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