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Merck
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Key Documents

5133

Sigma-Aldrich

Bovine Collagen Type I & III

from bovine hide, liquid, 10 mg/mL, suitable for cell culture, used for 3D hydrogel formation, FibriCol®

Synonyme(s) :

Sepharose 4B

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About This Item

Code UNSPSC :
12352202
Nomenclature NACRES :
NA.75

product name

FibriCol®, Collagen solution from Bovine hide, 97% Type I with the remainder of Type III collagen, suitable for cell culture

Source biologique

(Collagen solution from Bovine hide)

Niveau de qualité

100

Stérilité

sterile-filtered

Pureté

>99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)

Forme

solution

Conditionnement

pkg of 20 mL

Technique(s)

cell culture | mammalian: suitable

Solubilité

water: miscible

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Catégories apparentées

Description générale

FibriCol® collagen is approximately 97% Type I collagen with the remainder being comprised of Type III collagen. It contains a high monomer content as measured by gel permeation chromatography.

It is ideal for applications where high concentrations of collagen are needed. FibriCol® collagen is provided in a 20 mL volume and is contained in user-friendly packaging for use and storage. FibriCol® is sterile filtered and is supplied as a ready to use solution.

Application

FibriCol® has been used:

  • in the preparation of liposome-loaded co-gels to treat methicillin-resistant Staphylococcus aureus (MRSA) infections in vitro and in vivo
  • in the preparation of gelatin-methacrylate (gelMA)-collagen gels to study the effects of stiffness and fiber density on cellular behavior in breast cancer cell lines
  • in the preparation of collagen hydrogels to study its effects on macrophage response in partial thickness abdominal wall defect rat models

Informations légales

FibriCol is a registered trademark of Advanced BioMatrix, Inc.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Host macrophage response to injectable hydrogels derived from ECM and ?-helical peptides
Nazia M, et al.
Acta Biomaterialia, 111, 141-152 (2020)
Anthony J Berger et al.
Biomaterials, 141, 125-135 (2017-07-07)
The extracellular microenvironment provides critical cues that guide tissue development, homeostasis, and pathology. Deciphering the individual roles of these cues in tissue function necessitates the development of physically tunable culture platforms, but current approaches to create such materials have produced
Raj Kumar Thapa et al.
Acta biomaterialia, 103, 115-128 (2019-12-18)
Wound infections are a significant clinical problem affecting millions of people worldwide. Topically applied antibacterial formulations with longer residence time and controlled antimicrobial release would offer significant benefits for improved prevention and treatment of infected wounds. In this study, we

Articles

Attachment Factors for Three-dimensional Cell Culture

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

Attachment Factors for Three-dimensional Cell Culture

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

Attachment Factors for Three-dimensional Cell Culture

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

Attachment Factors for Three-dimensional Cell Culture

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

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