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Key Documents

42874

Sigma-Aldrich

Tetramethylrhodamine isothiocyanate–Dextran

average mol wt 40,000

Synonyme(s) :

TRITC-Dextran 40, TRITC-Dextran

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About This Item

Numéro MDL:
MFCD00132418
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.32

Source biologique

synthetic

Niveau de qualité

100

Forme

powder

Poids mol.

average mol wt 40,000

Ampleur du marquage

0.001-0.008 mol/mol TRITC glucose

Fluorescence

λex 550 nm; λem 577 nm±5 nm in 0.1 M Tris pH 8.0

Application(s)

cell analysis

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Description générale

Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 40, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.

Application

Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 40) is used as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular drug delivery.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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J David Symons et al.
Arteriosclerosis, thrombosis, and vascular biology, 22(5), 772-780 (2002-05-15)
High circulating concentrations of homocysteine (ie, hyperhomocysteinemia [Hhcy]) impair the vascular function of peripheral conduit arteries and arterioles perfusing splanchnic and skeletal muscle regions. The effects of HHcy on coronary resistance vessel function and other indexes of vascular function, ie
Andrea Kassner et al.
Neuroimaging clinics of North America, 21(2), 315-325 (2011-06-07)
The blood-brain barrier (BBB) is a functional concept to describe unique features of intracranial blood vessels that prevent many substances in the systemic circulation from entering the brain. In the setting of acute ischemic stroke, loss of blood-brain barrier (BBB)
Shuning Bian et al.
The Review of scientific instruments, 88(3), 034302-034302 (2017-04-05)
The development of a multimodal instrument capable of real-time in situ measurements of cavitation activity and effect in tissue mimicking phantoms during ultrasound and cavitation mediated drug delivery experiments is described here. The instrument features an acoustic arm that can
Weijun Tong et al.
The journal of physical chemistry. B, 109(27), 13159-13165 (2006-07-21)
Multilayer microcapsules showing unique charge-controlled permeability have been successfully fabricated by employing poly(styrene sulfonate) (PSS)-doped CaCO3 particles as templates. Encapsulation of the PSS molecules is thus achieved after core removal. Scanning force microscopy (SFM), UV-vis, Raman spectroscopy, and zeta-potential confirm
Kimberley J Reeves et al.
Journal of vascular research, 49(2), 132-143 (2012-01-21)
This study evaluated four fluorescent-protein conjugates to monitor microcirculatory variables using the murine cremaster muscle and determined acute and long-term responses to repeated administration of FITC-BSA [conjugated at the University of Sheffield (UoS)] within a dorsal microcirculatory chamber (DMC) in
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