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Key Documents

326M-1

Sigma-Aldrich

PSAP (PASE/4LJ) Mouse Monoclonal Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

PASE/4LJ, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (326M-14)
vial of 0.5 mL concentrate (326M-15)
bottle of 1.0 mL predilute (326M-17)
vial of 1.0 mL concentrate (326M-16)
bottle of 7.0 mL predilute (326M-18)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

Isotype

IgG1

Contrôle

prostate

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic

Informations sur le gène

human ... PSAP(5660)

Catégories apparentées

Description générale

Anti-PSAP reacts with prostatic acid phosphatase in the glandular epithelium of normal and hyperplastic prostate, carcinoma of the prostate, and metastatic cells of prostatic carcinoma. This marker may be helpful in pinpointing the site of origin in cases of metastatic carcinoma of the prostate, and is considered a more sensitive marker than PSA. However, it also offers less specificity. Nevertheless, PSAP complements PSA in the right clinical context.

Qualité


IVD
IVD
IVD
RUO

Liaison

PSAP Positive Control Slides, Product No. 326S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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N Kuroda et al.
Pathology international, 49(5), 457-461 (1999-07-27)
Signet-ring cell carcinoma (SRCC) of the prostate is a very rare neoplasm and there have been only 38 cases reported to date. Here the 39th case of prostatic SRCC containing a small amount of neutral mucin, prostatic specific antigen (PSA)
A A Elgamal et al.
Urology, 44(1), 84-90 (1994-07-01)
The aim of the study was to explore possible production of prostate-specific markers by the embryologically and physiologically related accessory male sex glands, other than the prostate. The accessory male sex glands of Cowper, Littre, and Morgagni were studied systematically
J I Epstein
The Urologic clinics of North America, 20(4), 757-770 (1993-11-01)
This article describes the immunoreactivity of PSA and PAP in non-neoplastic and neoplastic prostate tissue. Listed are examples of cross reactivity of PSA and PAP in non-neoplastic and neoplastic tissue from other organs. The use of PSA and PAP to
N Kimura et al.
Virchows Archiv. A, Pathological anatomy and histopathology, 410(3), 247-251 (1986-01-01)
Although prostate-specific acid phosphatase (PASP) has been recognized as a specific marker of tissue of prostatic origin, several investigators have pointed out that some of the carcinoid tumours and islet cell tumours of the pancreas reacted immunohistochemically to PSAP. We
E M Genega et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 13(11), 1186-1191 (2000-12-06)
Morphologic features alone can usually be used to distinguish prostatic adenocarcinoma and urothelial carcinoma of the urinary bladder. Poorly differentiated tumors, however, can occasionally have features of both neoplasms, making determination of site of origin difficult. No study has provided
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