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21879

Sigma-Aldrich

5(6)-Carboxyfluorescein diacetate

BioReagent, suitable for fluorescence, ≥90.0% (HPLC)

Synonyme(s) :

5(6)-Carboxy-di-O-acetylfluorescein

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About This Item

Formule empirique (notation de Hill):
C25H16O9
Numéro CAS:
124387-19-5
Poids moléculaire :
460.39
Numéro MDL:
MFCD00467494
Code UNSPSC :
12352108
ID de substance PubChem :
329752214
Nomenclature NACRES :
NA.32

Gamme de produits

BioReagent

Niveau de qualité

100

Pureté

≥90.0% (HPLC)

Forme

powder

Solubilité

DMSO: soluble

Fluorescence

λex 492 nm; λem 517 nm in 0.1 M Tris pH 8.0 (esterase)

Adéquation

suitable for fluorescence

Température de stockage

2-8°C

Chaîne SMILES 

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1.CC(=O)Oc6ccc7c(Oc8cc(OC(C)=O)ccc8C79OC(=O)c%10cccc(C(O)=O)c9%10)c6

InChI

1S/2C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25;1-12(26)31-14-6-8-18-20(10-14)33-21-11-15(32-13(2)27)7-9-19(21)25(18)22-16(23(28)29)4-3-5-17(22)24(30)34-25/h2*3-11H,1-2H3,(H,28,29)

Clé InChI

SWRGCNMDGRMQGB-UHFFFAOYSA-N

Description générale

5(6)-Carboxyfluorescein diacetate or CDFDA is a fluorescent oxidant sensing probe. It is an intracellular probe added to the cells as a pro-substrate, which upon hydrolysis by the esterase enzyme produces the fluorescent product called CDF.

Application

5(6)-Carboxyfluorescein diacetate (CFDA) is a dye which is been extensively utilized to label cultured neurons with the essential requirements, in a specific manner.

5(6)- Carboxyfluorescein diacetate (CFDA) is a viability probe that assesses enzymatic activity, which is necessary to activate its fluorescence, and cell-membrane integrity, which is necessary for the retention of their fluorescent product within the cell.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Zhuo Chen et al.
Journal of controlled release : official journal of the Controlled Release Society, 320, 469-483 (2020-01-29)
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The New phytologist, 215(2), 699-710 (2017-04-07)
The interactions of vector-virus-plant have important ecological and evolutionary implications. While the tripartite interactions have received some attention, little is known about whether vector infestation affects subsequent viral transmission and infection. Working with the whitefly Bemisia tabaci, begomovirus and tobacco/tomato
Rodrigo Anibal Mateos-Nava et al.
Drug and chemical toxicology, 40(4), 457-462 (2016-12-13)
Vanadium is a widely distributed metal in the Earth's surface and is released into the environment by either natural or anthropogenic causes. Vanadium (III) oxide (V
Tsui-Chun Hsu et al.
PloS one, 13(4), e0194866-e0194866 (2018-04-12)
Zearalenone (ZEN) is a mycotoxin produced by Fusarium species, which is one of the main animal feed contaminants causing reproductive disorders in livestock. The aim of this study was to evaluate the probiotic characteristics and ZEN removal ability of a
Zhiyuan Zhang et al.
The Plant cell, 29(8), 2027-2046 (2017-07-28)
Plasmodesmata (PDs) play vital roles in cell-to-cell communication and plant development. Emerging evidence suggests that sterols are involved in PD activity during cytokinesis. However, whether sterols contribute to PD gating between established cells remains unknown. Here, we isolated
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