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Key Documents

200-05N

Sigma-Aldrich

Human Umbilical Vein Endothelial Cells: HUVEC, neonatal

Synonyme(s) :

HUVEC cells

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About This Item

Code UNSPSC :
41106514
Nomenclature NACRES :
NA.81

Source biologique

human umbilicus (normal veins)

Niveau de qualité

Conditionnement

pkg of 500,000 cells

Fabricant/nom de marque

Cell Applications, Inc

Mode de croissance

Adherent

Caryotype

2n = 46

Morphologie

Endothelial

Technique(s)

cell culture | mammalian: suitable

Maladie(s) pertinente(s)

arthritis; diabetes; cancer; cardiovascular diseases

Conditions d'expédition

dry ice

Température de stockage

−196°C

Description générale

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Human Umbilical Vein Endothelial Cells (HUVEC) provide a classic model system to study many aspects of endothelial function and disease, such as normal, abnormal and tumor-associated angiogenesis, oxidative stress, hypoxia and inflammation related pathways in endothelia under normal and pathological conditions, cardiovascular-related complications associated with various diseases, mode of action and cardiovascular protection effects of various compounds, etc.

Origine de la lignée cellulaire

Vein

Application

angiogenesis, cell signaling pathways, migration, invasion, growth factors, tube formation, vascular homeostasis, modulation of blood vessel tone, regulate cell grwoth and ECM deposition, vasculoregulation

Composants

Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO

Notes préparatoires

  • Primary culture, >500,000 cells in Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 16 doublings

Procédure de repiquage

Please refer to the HUVEC Culture Protocol.

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d'importation et d'exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L'acheteur (c'est-à-dire l'utilisateur final) est tenu d'obtenir une autorisation d'importation auprès du Ministère français de la Recherche, mentionné à l'article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l'autorisation d'importation requise.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Clarisse Roblin et al.
International journal of molecular sciences, 22(6) (2021-04-04)
The world is on the verge of a major antibiotic crisis as the emergence of resistant bacteria is increasing, and very few novel molecules have been discovered since the 1960s. In this context, scientists have been exploring alternatives to conventional
Ziwei Tang et al.
International journal of endocrinology, 2021, 5575927-5575927 (2021-07-10)
It has been increasingly appreciated that G protein-coupled estrogen receptor 1 (GPER1) mediates both proinflammatory and anti-inflammatory response of estrogen. It is also involved in some rapid vascular effects of aldosterone in a mineralocorticoid receptor (MR) independent manner. However, whether
Wei Yan et al.
Frontiers in cell and developmental biology, 9, 616306-616306 (2021-04-09)
Oral squamous cell carcinoma (OSCC), accounting for two-thirds of head and neck cancer, is characterized by poor prognosis and a high rate of mortality. Exosomes have emerged as potential molecule-shuttle in intercellular communication, thereby regulating the physiological processes of recipient
Yi-Ting Yeh et al.
PLoS pathogens, 18(3), e1010309-e1010309 (2022-03-23)
The eggs of the parasitic blood fluke, Schistosoma, are the main drivers of the chronic pathologies associated with schistosomiasis, a disease of poverty afflicting approximately 220 million people worldwide. Eggs laid by Schistosoma mansoni in the bloodstream of the host

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Protocoles

Human Umbilical Vein Endothelial Cells (HUVEC) Culture Protocol. Storage. Preparation for Culturing. Store the cryovials in a liquid nitrogen storage tank immediately upon arrival.

Human Umbilical Vein Endothelial Cells (HUVEC) Culture Protocol. Storage. Preparation for Culturing. Store the cryovials in a liquid nitrogen storage tank immediately upon arrival.

Human Umbilical Vein Endothelial Cells (HUVEC) Culture Protocol. Storage. Preparation for Culturing. Store the cryovials in a liquid nitrogen storage tank immediately upon arrival.

Human Umbilical Vein Endothelial Cells (HUVEC) Culture Protocol. Storage. Preparation for Culturing. Store the cryovials in a liquid nitrogen storage tank immediately upon arrival.

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