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Merck
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Principaux documents

D137510

Sigma-Aldrich

N,N-Diméthylacétamide

ReagentPlus®, 99%

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About This Item

Formule linéaire :
CH3CON(CH3)2
Numéro CAS:
Poids moléculaire :
87.12
Beilstein:
1737614
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352111
ID de substance PubChem :
Nomenclature NACRES :
NA.21
Essai:
99%
pb:
164.5-166 °C (lit.)
Pression de vapeur:
2 mmHg ( 25 °C)
4 mmHg ( 38 °C)

Densité de vapeur

3 (vs air)

Niveau de qualité

Pression de vapeur

2 mmHg ( 25 °C)
4 mmHg ( 38 °C)

Gamme de produits

ReagentPlus®

Essai

99%

Forme

liquid

Température d'inflammation spontanée

914 °F

Limite d'explosivité

1.8 %, 100 °F
11.5 %, 160 °F

Indice de réfraction

n20/D 1.437 (lit.)

pH

4 (20 °C, 200 g/L)

pb

164.5-166 °C (lit.)

Pf

−20 °C (lit.)

Densité

0.937 g/mL at 25 °C (lit.)

Chaîne SMILES 

CN(C)C(C)=O

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

Clé InChI

FXHOOIRPVKKKFG-UHFFFAOYSA-N

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Description générale

N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene′s, vinyl resins, linear polyesters, acrylic fibers, plastics, pesticides, and synthetic leather. Additionally, it is utilized in the production of adhesives, films, and paint. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base.

Application

N,N-Dimethylacetamide can be used as a solvent in the synthesis of:
  • Cellulose-HA (hydroxyapatite) nanocomposites using microcrystalline cellulose, CaCl2, and NaH2PO4.
  • 5-hydroxymethylfurfural (HMF) from various carbohydrates and natural biopolymer lignocellulose in the presence of LiCl. 

It can also be used:
  • In the Pd-catalyzed regioselective synthesis of ketones from olefins using molecular oxygen.
  • As a solvent as well as a methylene source in the regioselective linkage of two imidazo[1,2-a] pyridines using Cu(OAc)2 catalyst.

Caractéristiques et avantages

N,N-Dimethylacetamide has
  • High dissolution power of various substrate.
  • High capacity to solvate anions.

Informations légales

Belle Chemical Company
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazardExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

147.2 °F - closed cup

Point d'éclair (°C)

64 °C - closed cup


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Lot/Batch Number

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Consulter la Bibliothèque de documents

Tony Reid et al.
The Lancet. Oncology, 16(9), 1133-1142 (2015-08-25)
Epigenetic alterations have been strongly associated with tumour formation and resistance to chemotherapeutic drugs, and epigenetic modifications are an attractive target in cancer research. RRx-001 is activated by hypoxia and induces the generation of reactive oxygen and nitrogen species that
S Sood et al.
Animal reproduction science, 129(1-2), 89-95 (2011-11-15)
Three experiments conducted to improve the survival of emu sperm during cryopreservation aimed to: (1) minimize chilling injury during the cooling phase; (2) determine the osmotic effects of dimethylacetamide (DMA), sucrose and trehalose; and (3) investigate the timing and nature
Wesley Walker et al.
Journal of the American Chemical Society, 135(6), 2076-2079 (2013-01-31)
A major challenge in the development of rechargeable Li-O(2) batteries is the identification of electrolyte materials that are stable in the operating environment of the O(2) electrode. Straight-chain alkyl amides are one of the few classes of polar, aprotic solvents
Jingshuai Yang et al.
ChemSusChem, 6(2), 275-282 (2013-01-11)
Covalently cross-linked polymer membranes were fabricated from poly(aryl sulfone benzimidazole) (SO(2)PBI) and poly(vinylbenzyl chloride) (PVBCl) as electrolytes for high-temperature proton-exchange-membrane fuel cells. The cross-linking imparted organo insolubility and chemical stability against radical attack to the otherwise flexible SO(2)PBI membranes. Steady
Fen Ran et al.
Acta biomaterialia, 7(9), 3370-3381 (2011-06-11)
An amphiphilic triblock co-polymer of poly(vinyl pyrrolidone)-b-poly(methyl methacrylate)-b-poly(vinyl pyrrolidone) (PVP-b-PMMA-b-PVP) was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. The block co-polymer can be directly blended with polyethersulfone (PES) using dimethylacetamide (DMAC) as the solvent to prepare flat sheet and

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