360457

Acétonitrile

≥99.5%, ACS reagent

• Synonyme(s) : ACN, Cyanométhane, Cyanure de méthyle, Éthylnitrile
• Formule linéaire : CH₃CN
• Numéro CAS: 75-05-8
• Poids moléculaire : 41.05
• Numéro Beilstein : 741857
• Numéro CE : 200-835-2
• Numéro MDL: MFCD00001878
• Code UNSPSC : 12191502
• eCl@ss : 39031501
• ID de substance PubChem : 329755257
• Nomenclature NACRES : NA.21

Propriétés

• product name: Acétonitrile, ACS reagent, ≥99.5%
• Qualité: ACS reagent
• Niveau de qualité: 100; 200
• Densité de vapeur: 1.41 (vs air)
• Pression de vapeur: 72.8 mmHg ( 20 °C)
• Pureté: ≥99.5%
• Forme: liquid
• Température d'inflammation spontanée: 973 °F
• Limite d'explosivité: 16 %
• Impuretés: ≤0.3% water; ≤0.6 μeq/g Titr. base; ≤8 μeq/g Titr. acid
• Résidus d'évap.: ≤0.005%
• Couleur: APHA: ≤10
• Indice de réfraction: n20/D 1.344 (lit.)
• Point d'ébullition: 81-82 °C (lit.)
• Pf: −45 °C (lit.)
• Densité: 0.786 g/mL at 25 °C (lit.)
• Format: neat
• Chaîne SMILES: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• Clé InChI: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Description

Description générale

Acetonitrile (MeCN, ACN) is an aliphatic nitrile that is commonly used as a reaction solvent as well as a chemical intermediate in organic synthesis. In many chromatographic techniques, MeCN is used as a mobile phase solvent due to its low viscosity, high elution strength, and miscibility in water.

Application

Acetonitrile can be used as a solvent in:      

• The solid-phase peptide synthesis.     
• The sialylation reactions.      
• The synthesis of copper nanoparticles by reduction of copper nitrate salt using NaBH₄. During the preparation, ACN acts as a protecting solvent, which prevents the oxidation of nanoparticles.      
• The preparation of diaryl selenides by Cu-catalyzed coupling reaction between aryl iodides and diphenyl diselenide. In this process, ACN also functions as a ligand for the copper catalyst to increase its catalytic activity.

Caractéristiques et avantages

ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302 + H312 + H332,H319
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 35.6 °F - closed cup
• Point d'éclair (°C): 2.0 °C - closed cup