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Y0000884

Carprofen for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Carprofen, 6-Chloro-α-methyl-9H-carbazole-2-acetic acid

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About This Item

Formule empirique (notation de Hill):
C15H12ClNO2
Numéro CAS:
53716-49-7
Poids moléculaire :
273.71
Numéro MDL:
MFCD00079028
Code UNSPSC :
41116107
ID de substance PubChem :
329831204
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

carprofen

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

Clé InChI

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Informations sur le gène

human ... PTGS2(5743)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carprofen for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301

Conseils de prudence

P301 + P330 + P331 + P310

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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S M Fox et al.
Journal of the American Veterinary Medical Association, 210(10), 1493-1498 (1997-05-15)
Most studies of nonsteroidal anti-inflammatory drugs (NSAID) do not demonstrate appreciable differences in efficacy. As awareness of the adverse effects associated with NSAID use increases, safety is becoming the primary concern among physicians when selecting NSAID for use by their
Arijit Ghosh et al.
PloS one, 9(5), e98143-e98143 (2014-05-24)
Blood-brain barrier (BBB) impairment in systemic inflammation leads to neuroinflammation. Several factors including cytokines, chemokines and signal transduction molecules are implicated in BBB dysfunction in response to systemic inflammation. Here, we have adopted a novel in vivo technique; namely, cerebral
Danielle L Freeborn et al.
Toxicology and applied pharmacology, 282(2), 184-194 (2014-12-09)
The electroencephalogram (EEG) is an apical measure, capable of detecting changes in brain neuronal activity produced by internal or external stimuli. We assessed whether pesticides with different modes of action produced different changes in the EEG of adult male Long-Evans
K R Lezak et al.
Psychoneuroendocrinology, 45, 11-20 (2014-05-23)
Single nucleotide polymorphisms (SNP) in the genes for pituitary adenylate cyclase-activating polypeptide (PACAP) and the PAC1 receptor have been associated with several psychiatric disorders whose etiology has been associated with stressor exposure and/or dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. In
H F Clarke et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(22), 7663-7676 (2014-05-30)
Schizophrenia is associated with upregulation of dopamine (DA) release in the caudate nucleus. The caudate has dense connections with the orbitofrontal cortex (OFC) via the frontostriatal loops, and both areas exhibit pathophysiological change in schizophrenia. Despite evidence that abnormalities in
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