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Y0000022

Succinate de sumatriptan

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

GR-43175, Succinate de 3-[2-(diméthylamino)éthyl]- N-méthyl-1H-indole-5-méthanesulfonamide

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About This Item

Formule empirique (notation de Hill):
C14H21N3O2S · C4H6O4
Numéro CAS:
103628-48-4
Poids moléculaire :
413.49
Numéro MDL:
MFCD00902856
Code UNSPSC :
41116107
ID de substance PubChem :
329830818
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sumatriptan

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

Clé InChI

PORMUFZNYQJOEI-UHFFFAOYSA-N

Informations sur le gène

human ... HTR1B(3351) , HTR1D(3352)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sumatriptan succinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Le succinate de sumatriptan est un agoniste des récepteurs de la sérotonine 5-HT1.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1642201

Succinate de sumatriptan, United States Pharmacopeia (USP) Reference Standard

1642212

Sumatriptan Succinate Related Compound A, United States Pharmacopeia (USP) Reference Standard

Y0000026

Sumatriptan impurity mixture, European Pharmacopoeia (EP) Reference Standard

Y0000027

Succinate de sumatriptan, European Pharmacopoeia (EP) Reference Standard

1642154

Sumatriptan, United States Pharmacopeia (USP) Reference Standard

1642256

Sumatriptan succinate Related Impurities, United States Pharmacopeia (USP) Reference Standard

1642223

Composé C apparenté au succinate de sumatriptan, United States Pharmacopeia (USP) Reference Standard

BP950

Succinate de sumatriptan, British Pharmacopoeia (BP) Reference Standard

PHR2580

Succinate de sumatriptan, pharmaceutical secondary standard, certified reference material

PHR2914

Sumatriptan Succinate Related Compound C, certified reference material, pharmaceutical secondary standard

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Warning

Mentions de danger

H361d,H412

Classification des risques

Aquatic Chronic 3 - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Toshihiko Tomita et al.
Journal of gastroenterology and hepatology, 28(1), 106-111 (2012-09-20)
Scintigraphy is a useful noninvasive technique for assessment of gastric motility, especially emptying, but there is little knowledge of use of the technique to assess gastric accommodation. Therefore, to clarify the usefulness of scintigraphy as a technique for assessing gastric
Benjamin W Friedman et al.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(10), 1151-1157 (2012-09-22)
Patients who use an emergency department (ED) for acute migraine headaches have higher migraine disability scores, lower socioeconomic status, and are unlikely to have used a migraine-specific medication prior to presentation to the ED. The objective was to determine if
Babak Bakhshayesh et al.
The American journal of emergency medicine, 31(3), 540-544 (2013-02-06)
The objective of this study is to compare the efficacy and tolerability of intravenous valproic acid (iVPA) with intramuscular metoclopramide + subcutaneous (SQ) sumatriptan for prolonged acute migraine. Intravenous valproic acid has been explored as a possible treatment of acute
Mohammad Sohail Asghar
Danish medical journal, 59(7), B4489-B4489 (2012-07-05)
Over the last decades MRI has proved to be very useful in the field of drug development and drug discovery. Pharmacological MRI (phMRI) explores the interaction between brain physiology, neuronal activity and drugs. The BOLD signal is an indirect method
M J Cózar-Bernal et al.
Journal of pharmaceutical and biomedical analysis, 72, 251-260 (2012-10-16)
In this paper, a novel, precise, specific, accurate and rapid reversed-phase high performance liquid chromatographic method was developed, optimized and validated for determining sumatriptan succinate in niosomes with the best chromatographic peak resolution, reduced run time and low cost of
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