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T0050000

Terbutaline sulfate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Terbutaline hemisulfate salt, 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol, 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol hemisulfate salt

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About This Item

Formule linéaire :
C12H19NO3 · 1/2H2SO4
Numéro CAS:
23031-32-5
Poids moléculaire :
274.32
Numéro MDL:
MFCD00079584
Code UNSPSC :
41116107
ID de substance PubChem :
329826582
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

terbutaline

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

OS(O)(=O)=O.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c2cc(O)cc(O)c2

InChI

1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)

Clé InChI

KFVSLSTULZVNPG-UHFFFAOYSA-N

Informations sur le gène

human ... ADRB2(154)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Terbutaline sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H361,H370

Classification des risques

Repr. 2 - STOT SE 1

Organes cibles

Cardio-vascular system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Adel H Mansur et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(10), 1076-1082 (2014-07-16)
Long-term subcutaneous or intravenous infusion of terbutaline has been used to stabilize asthma in patients enduring frequent hospital admissions due to severe asthma despite maximum therapy. However, this treatment is not supported by significant body of evidence. To study long-term
John P Elliott et al.
The Journal of reproductive medicine, 58(3-4), 123-131 (2013-04-02)
Beta2-adrenergic agonist medications such as albuterol and terbutaline are often prescribed during pregnancy to treat conditions such as asthma, pulmonary disease, preterm labor, or acute non-reassuring fetal heart rate abnormalities during labor. Recently a review article questioned the safety of
F Lam et al.
Obstetrical & gynecological survey, 53(11 Suppl), S85-S95 (1998-11-13)
beta-mimetics have been prescribed by physicians to arrest or prevent premature labor for more than 20 years. Although not approved by the Food and Drug Administration (FDA) for tocolytic use, terbutaline sulfate has been the most widely prescribed beta-mimetic in
C H Scoggin
Clinical therapeutics, 6(5), 603-612 (1984-01-01)
Terbutaline sulfate, a relatively selective beta2 agonist, is indicated for the treatment of bronchospasm associated with chronic obstructive pulmonary disease. Studies have shown that when administered via an aerosol, terbutaline has a rapid onset, a prolonged duration of action, and
Srinivas R B Behara et al.
Journal of pharmaceutical sciences, 103(2), 465-477 (2013-12-07)
High-efficiency dry powder inhalers (DPIs) were developed and tested for use with carrier-free formulations across a range of different inhalation flow rates. Performance of a previously reported DPI was compared with two new designs in terms of emitted dose (ED)
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