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SMB00981

Sigma-Aldrich

2-Hydroxymelatonin

≥95% (HPLC)

Synonyme(s) :

2-OH MEL, 2-OHM, 2-OHMET, 2OHM, N-[2-(2,3-Dihydro-5-methoxy-2-oxo-1H-indol-3-yl)ethyl]acetamide, N-[2-(2-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide, AMIO

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About This Item

Formule empirique (notation de Hill):
C13H16N2O3
Numéro CAS:
229018-17-1
Poids moléculaire :
248.28
Numéro MDL:
MFCD30187118
Code UNSPSC :
12352205
Nomenclature NACRES :
NA.21

Niveau de qualité

200

Pureté

≥95% (HPLC)

Forme

solid

Température de stockage

2-8°C

Description générale

Melatonin (MT) is metabolized into several derivatives, including N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N1-acetyl-5-methoxykynuramine (AMK), 6-hydroxymelatonin, 2-hydroxymelatonin, 3-hydroxymelatonin, and cyclic 3-hydroxymelatonin. MT and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants.

Application

Metabolomics research

Autres remarques

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Anis Ali Shah et al.
Chemosphere, 243, 125308-125308 (2019-11-14)
Cadmium level is continuously increasing in agricultural soils mainly due to anthropogenic activities. Cadmium is one of the most phytotoxic metals in the soils. The present study investigates the possible role of 2-hydroxymelatonin (2-OHMT) in assuagement of Cd-toxicity in cucumber
Sung Ho Lee et al.
Biochemical and biophysical research communications, 527(4), 941-946 (2020-05-23)
2-Hydroxymelatonin is a metabolite produced when melatonin 2-hydroxylase catalyzes melatonin. Recent studies have reported the important roles of melatonin in bone metabolism. However, the roles of 2-hydroxymelatonin in bone metabolism remains poorly understood. The purpose of this study is to
Kyoungwhan Back
The Plant journal : for cell and molecular biology, 105(2), 376-391 (2020-07-10)
Melatonin is a multifunctional biomolecule found in both animals and plants. In this review, the biosynthesis, levels, signaling, and possible roles of melatonin and its metabolites in plants is summarized. Tryptamine 5-hydroxylase (T5H), which catalyzes the conversion of tryptamine into
Ewy A Mathé et al.
Cancer research, 74(12), 3259-3270 (2014-04-17)
Lung cancer remains the most common cause of cancer deaths worldwide, yet there is currently a lack of diagnostic noninvasive biomarkers that could guide treatment decisions. Small molecules (<1,500 Da) were measured in urine collected from 469 patients with lung

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