PHR1638

Alfuzosin hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, Uroxatral hydrochloride
• Formule empirique (notation de Hill): C₁₉H₂₇N₅O₄ · HCl
• Numéro CAS: 81403-68-1
• Poids moléculaire : 425.91
• Numéro MDL: MFCD00879135
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823527
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to Ph. Eur. A0325800; traceable to USP 1012917
• Famille d'API: alfuzosin
• CofA (certificat d'analyse): current certificate can be downloaded
• Conditionnement: ampule of 1 × 1 g
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3
• InChI: 1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
• Clé InChI: YTNKWDJILNVLGX-UHFFFAOYSA-N
• Informations sur le gène: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

Description

Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Alfuzosin hydrochloride may be used as a pharmaceutical reference standard for the quantification of alfuzosin hydrochloride levels in pharmaceutical formulations by reverse phase high-performance liquid chromatography (RP-HPLC), high performance thin layer chromatography (HPTLC) and spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Actions biochimiques/physiologiques

Alfuzosin hydrochloride is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA5304 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable