PHR1583

Megestrol acetate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : 17α-acétoxy-6-méthyl-4,6-pregnadiène-3,20-dione, 17α-hydroxy-6-méthyl-4,6-pregnadiène-3,20-dione 17-acétate
• Formule empirique (notation de Hill): C₂₄H₃₂O₄
• Numéro CAS: 595-33-5
• Poids moléculaire : 384.51
• Numéro Beilstein : 1917291
• Numéro CE : 209-864-5
• Numéro MDL: MFCD00056470
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823491
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to BP 223; traceable to Ph. Eur. Y0001514; traceable to USP 1379106
• Famille d'API: megesterol
• CofA (certificat d'analyse): current certificate can be downloaded
• Conditionnement: pkg of 1 g
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C
• InChI: 1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1
• Clé InChI: RQZAXGRLVPAYTJ-GQFGMJRRSA-N
• Informations sur le gène: human ... PGR(5241)

Description

Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Megestrol Acetate is a progestogen drug indicated for the palliative treatment of endometrial carcinoma and breast cancer. The administration of the drug is usually done orally as a solid dosage form.

Application

Megestrol Acetate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, oral contraceptives and suspensions by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA4562 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360FD
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable