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O5879

Supelco

Ornidazole

analytical standard

Synonyme(s) :

1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole

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About This Item

Formule linéaire :
C7H10N3O3Cl
Numéro CAS:
16773-42-5
Poids moléculaire :
219.63
Numéro CE :
240-826-0
Numéro MDL:
MFCD00057960
Code UNSPSC :
41116107
ID de substance PubChem :
329818917
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

200

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Chaîne SMILES 

Cc1ncc(n1CC(O)CCl)[N+]([O-])=O

InChI

1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3

Clé InChI

IPWKIXLWTCNBKN-UHFFFAOYSA-N

Application

Ornidazole has been used as a standard in the determination of traces of ornidazole in samples of aquaculture tissue using ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number
0000395414
0000388136
0000388136
0000395414
0000272704

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Fehmi Tabak et al.
Liver international : official journal of the International Association for the Study of the Liver, 23(5), 351-354 (2004-01-08)
Metronidazole and ornidazole, synthetic nitroimidazole derivatives, are used in the treatment of infections caused by anaerobic bacteria and protozoa. The drugs are well tolerated and serious side effects are very rarely encountered. Hepatotoxicity is a rare side effect and hitherto
Nathalie Mahé et al.
Journal of pharmaceutical sciences, 100(6), 2258-2266 (2011-01-20)
The solid-state properties of antiprotozoal ternidazole (3-(2-methyl-5-nitroimidazol-1-yl)-propan-1-ol) have been studied. Crystals are triclinic in the temperature interval between 100 and 333 K (melting point) with two different molecular conformations present in the asymmetric unit (Z' = 2) and two of
Subhash S Vaghani et al.
Carbohydrate research, 347(1), 76-82 (2011-11-22)
In the present study, carboxymethyl chitosan was prepared from chitosan, crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for colon targeted drug delivery of ornidazole. Ornidazole was incorporated at the time of crosslinking of carboxymethyl chitosan. The
Kriti Shivhare et al.
International journal of biological macromolecules, 106, 775-783 (2017-08-19)
Molecular self-assembly of biodegradable amphiphilic polymers allows rational design of biocompatible nanomaterials for drug delivery. Use of substituted polysaccharides for such applications offers the ease of design and synthesis, and provides higher biofunctionality and biocompatibility to nanomaterials. The present work
Marta Dolores Mudry et al.
Mutation research, 721(1), 108-113 (2011-01-25)
The genotoxicity of two nitroimidazole derivatives, ornidazole (ONZ) and metronidazole (MTZ) in the peripheral blood lymphocytes of Cebus libidinosus (CLI) (Primates, Cebidae) was assessed. Endpoints measured included sister chromatid exchange (SCE) frequency, cell proliferation kinetics (CPK), replication index (RI), mitotic
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