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N0900000

Nitrazepam

European Pharmacopoeia (EP) Reference Standard

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About This Item

Formule empirique (notation de Hill):
C15H11N3O3
Numéro CAS:
146-22-5
Poids moléculaire :
281.27
Numéro MDL:
MFCD00058577
Code UNSPSC :
41116107
ID de substance PubChem :
329818469
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

nitrazepam

Fabricant/nom de marque

EDQM

Contrôle du médicament

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI

1S/C15H11N3O3/c19-14-9-16-15(10-4-2-1-3-5-10)12-8-11(18(20)21)6-7-13(12)17-14/h1-8H,9H2,(H,17,19)

Clé InChI

KJONHKAYOJNZEC-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nitrazepam EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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János Gidai et al.
Pharmacoepidemiology and drug safety, 19(2), 175-182 (2009-12-10)
To evaluate the teratogenic effect of very large doses of nitrazepam in children born to pregnant women who attempted suicide and to check the feasibility of self-poisoning pregnant women model. Comparative analysis of exposed children and their unexposed sibs born
Mihalj Posa et al.
Talanta, 83(5), 1634-1642 (2011-01-18)
Linear dependence between temperature (t) and retention coefficient (k, reversed phase HPLC) of bile acids is obtained. Parameters (a, intercept and b, slope) of the linear function k=f(t) highly correlate with bile acids' structures. Investigated bile acids form linear congeneric
Shin Tokunaga et al.
Journal of pharmacological sciences, 103(2), 201-206 (2007-02-09)
The present study was undertaken to investigate the effects of some H(1)-antagonists on the sleep-wake cycle in sleep-disturbed rats in comparison with those of nitrazepam. Electrodes were chronically implanted into the frontal cortex and the dorsal neck muscle of rats
Ingebjørg Gustavsen et al.
Sleep medicine, 9(8), 818-822 (2008-01-30)
Despite the high prescription rate of benzodiazepine-like hypnotics (z-hypnotics), there is limited information on the road traffic accident risk associated with the use of these drugs. We wanted to investigate whether filling a prescription for zopiclone or zolpidem was associated
Mihalj Poša et al.
Colloids and surfaces. B, Biointerfaces, 86(2), 285-291 (2011-05-07)
The formation of mixed micelles built of 7,12-dioxolithocholic and the following hydrophobic bile acids was examined by conductometric method: cholic (C), deoxycholic (D), chenodeoxycholic (CD), 12-oxolithocholic (12-oxoL), 7-oxolithocholic (7-oxoL), ursodeoxycholic (UD) and hiodeoxycholic (HD). Interaction parameter (β) in the studied
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