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M1824990

Metoclopramide

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Methoxychloroprocainamide

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About This Item

Formule empirique (notation de Hill):
C14H22ClN3O2
Numéro CAS:
364-62-5
Poids moléculaire :
299.80
Numéro Beilstein :
1884366
Numéro MDL:
MFCD00211338
Code UNSPSC :
41116107
ID de substance PubChem :
329817892
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

metoclopramide

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC

InChI

1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)

Clé InChI

TTWJBBZEZQICBI-UHFFFAOYSA-N

Informations sur le gène

human ... DRD2(1813) , HTR3A(3359) , HTR4(3360)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metoclopramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1132

Metoclopramide Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1440808

Metoclopramide hydrochloride, United States Pharmacopeia (USP) Reference Standard

M1825010

N,N-Diéthyléthylènediamine, European Pharmacopoeia (EP) Reference Standard

M1825000

Metoclopramide hydrochloride, European Pharmacopoeia (EP) Reference Standard

M1824995

Metoclopramide impurity A, European Pharmacopoeia (EP) Reference Standard

1440820

Metoclopramide Related Compound B, United States Pharmacopeia (USP) Reference Standard

1440841

Metoclopramide Related Compound D, United States Pharmacopeia (USP) Reference Standard

1440819

Metoclopramide Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP357

Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2283

Metoclopramide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2284

Metoclopramide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2285

Metoclopramide Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2286

Metoclopramide Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2287

Methyl 4-(Acetylamino)-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2506

Metoclopramide Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2507

Metoclopramide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2508

Methyl 4-Amino-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Acute dystonic reaction caused by metoclopramide, versus tetanus.
Kyra Dingli et al.
BMJ (Clinical research ed.), 334(7599), 899-900 (2007-04-28)
B M Mishriky et al.
British journal of anaesthesia, 108(3), 374-383 (2012-02-07)
Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea
Robert J Surawski et al.
Psychosomatics, 52(5), 403-409 (2011-09-13)
Metoclopramide is an anti-emetic and gastrointestinal pro-motility agent associated with well-known neuropsychiatric adverse effects, such as dyskinesia, akathisia, and depression. It has never been reported to be associated with homicidal ideation. The authors review the literature on metoclopramide-induced adverse neuropsychiatric
Paul M Simpson et al.
Emergency medicine Australasia : EMA, 23(4), 452-457 (2011-08-10)
The objective of the present study was to conduct a systematic review and meta-analysis of randomized controlled trials, comparing metoclopramide with placebo, for preventing vomiting in patients who have received i.v. morphine for acute pain in the emergency setting, and
P Jay Pasricha et al.
Nature clinical practice. Gastroenterology & hepatology, 3(3), 138-148 (2006-03-03)
Metoclopramide, the only drug approved by the FDA for treatment of diabetic gastroparesis, but used off-label for a variety of other gastrointestinal indications, has many potentially troublesome adverse neurologic effects, particularly movement disorders. In this article, we comprehensively review the
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