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H1450000

Hyoscine butylbromide

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(−)-Scopolamine N-butyl bromide, (−)-N-Butylscopolamine bromide, Hyoscine N-butyl bromide

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About This Item

Formule empirique (notation de Hill):
C21H30BrNO4
Numéro CAS:
149-64-4
Poids moléculaire :
440.37
Numéro MDL:
MFCD00078561
Code UNSPSC :
41116107
ID de substance PubChem :
329815165
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

hyoscine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[Br-].[H][C@@]12C[C@H](C[C@@]([H])([C@]3([H])O[C@]13[H])[N+]2(C)CCCC)OC(=O)[C@H](CO)c4ccccc4

InChI

1S/C21H30NO4.BrH/c1-3-4-10-22(2)17-11-15(12-18(22)20-19(17)26-20)25-21(24)16(13-23)14-8-6-5-7-9-14;/h5-9,15-20,23H,3-4,10-13H2,1-2H3;1H/q+1;/p-1/t15-,16-,17-,18+,19-,20+,22?;/m1./s1

Clé InChI

HOZOZZFCZRXYEK-GSWUYBTGSA-M

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hyoscine butylbromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

H1500000

Hyoscine hydrobromide, European Pharmacopoeia (EP) Reference Standard

Y0000483

Hyoscine, European Pharmacopoeia (EP) Reference Standard

Y0000448

Hyoscine hydrobromide impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000484

Hyoscine impurity A, European Pharmacopoeia (EP) Reference Standard

1610001

Scopolamine hydrobromide, United States Pharmacopeia (USP) Reference Standard

PHR1470

Scopolamine Hydrobromide, Pharmaceutical Secondary Standard; Certified Reference Material

BP198

Hyoscine butylbromide, British Pharmacopoeia (BP) Reference Standard

BP199

Hyoscine hydrobromide, British Pharmacopoeia (BP) Reference Standard

Y0001983

Hyoscine butylbromide for system suitability, European Pharmacopoeia (EP) Reference Standard

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 + H332

Classification des risques

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Guido N Tytgat
Drugs, 67(9), 1343-1357 (2007-06-06)
Abdominal cramping and pain is a frequent problem in the adult population of Western countries, with an estimated prevalence of < or =30%. Hyoscine butylbromide (scopolamine butylbromide) [Buscopan/Buscapina] is an antispasmodic drug indicated for the treatment of abdominal pain associated
Andrew A Plumb et al.
AJR. American journal of roentgenology, 203(4), W400-W407 (2014-09-24)
The purpose of this article is to describe the MRI findings associated with lymphoid nodular hyperplasia at MR enterography and test the ability of radiologists to differentiate healthy control subjects from patients with Crohn disease (CD). Ethical approval was granted
K Mackway-Jones et al.
Emergency medicine journal : EMJ, 20(3), 267-267 (2003-05-16)
A short cut review was carried out to establish whether buscopan (hyoscine butylbromide) is better than analgesics at controlling pain in abdominal colic. A total of 31 papers were found using the reported search, of which none presented any evidence
Timur H Kuru et al.
Journal of computer assisted tomography, 38(4), 558-564 (2014-04-16)
To compare 2 previously presented algorithms for extracting parameters from intravoxel incoherent motion (IVIM) studies and investigate them in the context of tissue differentiation. Magnetic resonance imaging (MRI) was performed in 23 patients without histologically proven prostate carcinoma (PCa) and
Guido N Tytgat
Current medical research and opinion, 24(11), 3159-3173 (2008-10-15)
Being a quaternary ammonium compound derived from scopolamine, the alkaloid hyoscine butylbromide (HBB) exerts anticholinergic effects without side effects related to the central nervous system because it does not pass the blood-brain barrier. Clinical experience with this antispasmodic dates back
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