95212

L-acide ascorbique

tested according to Ph. Eur.

• Synonyme(s) : Acide L-thréoascorbique, Facteur anti-scorbut, Vitamine C
• Formule empirique (notation de Hill): C₆H₈O₆
• Numéro CAS: 50-81-7
• Poids moléculaire : 176.12
• Numéro Beilstein : 84272
• Numéro CE : 200-066-2
• Numéro MDL: MFCD00064328
• Code UNSPSC : 12352205
• ID de substance PubChem : 329770428
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Agence: USP/NF; tested according to Ph. Eur.
• Pureté: 99.0-100.5%
• Forme: solid
• Couleur: white to off-white
• pH: 1.0-2.5 (25 °C, 176 g/L in water)
• Pf: 190-194 °C (dec.)
• Solubilité: water: soluble 176 g/L at 20 °C
• Chaîne SMILES: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• Clé InChI: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
• Informations sur le gène: human ... SLC23A2(9962)

Description

Description générale

L-Ascorbic acid is the most biologically active form of ascorbic acid. It is hydrophilic and an unstable compound. L-Ascorbic acid contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid, also referred to as Vitamin C, is a water-soluble vitamin. Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation. Vitamin C is a part of citrus fruits, such as broccoli, strawberries, turnip.

Application

• Targeted screening of multiple anti-inflammatory components from Chrysanthemi indici Flos by ligand fishing with affinity UF-LC/MS: This study investigates the application of L-Ascorbic acid in enhancing the screening of anti-inflammatory compounds, utilizing its properties to stabilize reactive samples in cell cultures (Huang et al., 2024).


• Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso: Demonstrates the use of L-Ascorbic acid in the evaluation of antioxidant properties of plant extracts, which is crucial in the pharmaceutical research of natural products (Kabore et al., 2024).

Actions biochimiques/physiologiques

_L-Ascorbic acid functions according to its oxido-reduction property. It is a co-factor for hydroxylation. The biochemical actions of L-ascorbic acid is dependent on the activity of monoxygenase. It is involved in carnitine, collagen synthesis and production of neurotransmitters. Vitamin C exhibits anti-oxidant properties. Vitamin C plays a role in providing protection against photoaging and anti-aging effect. Deficiency of vitamin C leads to scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)