25107

Potassium citrate tribasic monohydrate

meets analytical specification of Ph. Eur., BP, FCC, E332, 99-100.5% (calc with ref. to anhyd. subst.)

• Synonyme(s) : Citric acid tripotassium salt, Tripotassium citrate
• Formule linéaire : HOC(COOK)(CH₂COOK)₂ · H₂O
• Numéro CAS: 6100-05-6
• Poids moléculaire : 324.41
• Numéro Beilstein : 3924344
• Numéro CE : 231-905-0
• Numéro MDL: MFCD00150442
• Code UNSPSC : 12352100
• ID de substance PubChem : 57648111
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 200
• Pureté: 99-100.5% (calc with ref. to anhyd. subst.)
• Forme: powder or crystals
• Qualité: meets analytical specification of Ph. Eur., BP, FCC, E332
• Impuretés: ≤0.0005% heavy metals (as Pb); 4-6% water (Karl Fischer)
• Perte: 3-6 loss on drying, 180°C
• pH: 7-9 (20 °C, 5%)
• Pf: 275 °C (dec.) (lit.)
• Solubilité: glycerol: soluble 1 gm in 2.5 ml; water: soluble 1 gm in 0.65 ml; alcohol: insoluble
• Traces d'anions: chloride (Cl^-): ≤30 mg/kg; oxalate (as oxalic acid): ≤100 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: As: ≤1 mg/kg; Cu: ≤10 mg/kg; Fe: ≤10 mg/kg; Hg: ≤1 mg/kg; Na: ≤3000 mg/kg; Pb: ≤1 mg/kg; Zn: ≤10 mg/kg
• Adéquation: in accordance for appearance of solution; passes test for reaction against H₂SO₄
• Application(s): pharmaceutical (small molecule)
• Chaîne SMILES: O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3
• Clé InChI: PJAHUDTUZRZBKM-UHFFFAOYSA-K

Description

Application

Potassium citrate tribasic monohydrate has been used for preparing citrate-supplemented water for feeding the Car5A, Car5B, and DKO breeding pairs of mice. Citrate supplementation enhances the perinatal death in mice. It is a citrate-based salt used as a phase constituent for characterizing ionic-liquid-based aqueous biphasic systems (ABS) and as a buffering agent.

Actions biochimiques/physiologiques

Potassium citrate tribasic monohydrate is the potassium salt of citric acid. It enhances the bone density hence used in the treatment of osteoporosis. Additionally, it neutralizes the protein-induced metabolic acidosis.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)