03440

N-Ethyldiisopropylamine

BASF quality, ≥98.0%

• Synonyme(s) : N,N-Diisopropylethylamine, Hünigs base
• Formule linéaire : CH₃CH₂N[CH(CH₃)₂]₂
• Numéro CAS: 7087-68-5
• Poids moléculaire : 129.24
• Numéro Beilstein : 605301
• Numéro CE : 230-392-0
• Numéro MDL: MFCD00008868
• Code UNSPSC : 12352100
• ID de substance PubChem : 329747703
• Nomenclature NACRES : NA.21

Propriétés

• Qualité: BASF quality
• Niveau de qualité: 200
• Pureté: ≥98.0%
• Forme: liquid
• Impuretés: ≤0.5% water
• Indice de réfraction: n20/D 1.414
• Point d'ébullition: 126-128 °C (lit.)
• Densité: 0.755 g/mL at 20 °C (lit.); 0.755 g/mL at 20 °C; 0.757 g/mL at 25 °C (lit.)
• Groupe fonctionnel: amine
• Chaîne SMILES: CCN(C(C)C)C(C)C
• InChI: 1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3
• Clé InChI: JGFZNNIVVJXRND-UHFFFAOYSA-N

Description

Description générale

N,N-Diisopropylethylamine (DIPEA), also known as Hunig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed in substitution reactions, alkylations, and amide couplings, etc. DIPEA is also used as a base in the Pd catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.

Application

• Catalytic activity in dioxygen reduction: A study utilized Mn complexes with pendent proton donor relays and added base, including N-Ethyldiisopropylamine, to control product selectivity during dioxygen reduction, providing insights into catalytic mechanisms and potential industrial applications (Cook et al., 2024).


• Three-dimensional imaging in medical applications: N-Ethyldiisopropylamine was mentioned in the context of its role in improving the resolution of three-dimensional imaging techniques based on computed tomography angiography (CTA), crucial for preoperative perforator selection in reconstructive surgery (Su et al., 2024).


• Synthesis of Spirocyclopropane-Containing Compounds: Research demonstrated the application of N-Ethyldiisopropylamine in the synthesis of spirocyclopropane-containing 4H-pyrazolo[1,5-a]indoles through alkylative dearomatization and intramolecular N-imination, highlighting its utility in complex organic synthesis (Huang et al., 2023).

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS05,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302,H318,H331,H335,H411
• Conseils de prudence: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.1 °F
• Point d'éclair (°C): 9.5 °C
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter