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Merck
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Key Documents

OP188

Sigma-Aldrich

Anti-FAP Mouse mAb (F11-24)

liquid, clone F11-24, Calbiochem®

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

F11-24, monoclonal

Forme

liquid

Ne contient pas

preservative

Espèces réactives

human

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG1

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... FAP(2191)

Description générale

Anti-FAP, mouse monoclonal, clone F11-24, recognizes fibroblast activation protein in human. It is validated for use in flow cytometry, immunoprecipitation, & immunohistochemistry (frozen sections).
Protein A purified mouse monoclonal antibody. Recognizes human fibroblast activation protein (FAP).
Recognizes fibroblast activation protein (FAP).

Immunogène

HEK293 cells transfected with an expression vector encoding full-length human FAP
Human

Application

Flow Cytometry (see comments)

Frozen Sections (1-5 µg/ml)

Immunoprecipitation (see comments)

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In PBS.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Remarque sur l'analyse

Positive Control
Reactive human fibroblasts, glucagon-producing A cells

Autres remarques

Does not react with resting fibroblasts of normal organ mesenchyme or parenchymal cells, except for the glucagon-producing A cells found in the pancreatic islets. This antibody has also been reported to work for flow cytometry and immunoprecipitation. Antibody should be titrated for optimal results in individual systems.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Larissa Belov et al.
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Sarah M Ridge et al.
International journal of cancer, 142(10), 2056-2067 (2017-12-22)
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Marta Trüb et al.
Journal for immunotherapy of cancer, 8(2) (2020-07-04)
The costimulatory receptor 4-1BB (CD137, TNFRSF9) plays an important role in sustaining effective T cell immune responses and is investigated as target for cancer therapy. Systemic 4-1BB directed therapies elicit toxicity or low efficacy, which significantly hampered advancement of 4-1BB-based

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