MAB805
Anti-Adenovirus (Blend) Coating Antibody, clone 2/6, and 20/11
ascites fluid, Chemicon®, from mouse
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
ascites fluid
Clone
2/6, monoclonal
20/11, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
Isotype
IgG1κ
Conditions d'expédition
wet ice
Description générale
Adenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.
Spécificité
Reactive with all 41 serotypes of Adenovirus.
Immunogène
Adeno 3
Application
Anti-Adenovirus (Blend) Coating Antibody, clone 2/6 & 20/11 is an antibody against Adenovirus (Blend) Coating for use in ELISA, IF, IH, IH(P).
EIA: 1:1000
IFA: 1:200
Immunohistochemistry: 1:400 - 1:1000 for formalin fixed paraffin-embedded or frozen tissue.
Optimal working dilutions must be determined by end user.
IFA: 1:200
Immunohistochemistry: 1:400 - 1:1000 for formalin fixed paraffin-embedded or frozen tissue.
Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Forme physique
Ascites fluid containing no preservatives.
Unpurified
Stockage et stabilité
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Remarque sur l'analyse
Control
Adenovirus Control Slides, Catalogue Number 5009-5
Adenovirus Control Slides, Catalogue Number 5009-5
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Silencing E1A mRNA by RNA interference inhibits adenovirus replication.
Y-S Chung,M-K Kim,W-J Lee,C Kang
Archives of Virology null
R Alemany et al.
Methods in molecular medicine, 35, 395-412 (2000-01-01)
It is important to analyze to what extent these random or designed mutations abrogate viral replication in normal cells because a tightly controlled vector could be injected at higher doses intratumorally or even systemically. On the other hand, it is
Yue-Hong Shen et al.
PloS one, 11(1), e0147173-e0147173 (2016-01-23)
CAR is a transmembrane protein that is expressed in various epithelial and endothelial cells. CAR mediates adenoviral infection, as well as adenovirus-mediated oncolysis of AxdAdB-3, an E1A/E1B double-restricted oncolytic adenovirus, in prostate cancer cells. This study further assessed the therapeutic
Oncolytic virotherapy for prostate cancer by E1A, E1B mutant adenovirus.
Makoto Satoh, Hua Wang, Shigeto Ishidoya, Hisashi Abe, Takuya Moriya, Hirofumi Hamada, Yoichi Arai
Urology null
Ran-Yi Liu et al.
Anatomical record (Hoboken, N.J. : 2007), 296(12), 1833-1841 (2013-10-19)
An E1B55K-attenuated adenovirus, dl1520, has been shown to replicate selectively in and lyse tumor cells. In this study, the antitumor activities of dl1520, alone or in combination with the chemotherapeutic agent cisplatin, were investigated in nasopharyngeal carcinoma (NPC) cells. The
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