ABN472

Anti-TFEB Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35, TFEB
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): western blot: suitable
• Numéro d'accès UniProt: P19484
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TFEB(7942)

Description

Description générale

Transcription factor EB (TFEB) is a member of the MiT/TFE family of transcription factors that is translocated in a subset of renal tumors. It plays an important role in the signal transduction process required for normal vascularization of the placenta. TFEB specifically recognizes and binds the E-box sequence (5′-CANNTG-3′) and CLEAR box sequence (5′-GTCACGTGAC-3′).

Immunogène

KLH-conjugated linear peptide corresponding to human TFEB.

Application

Detect TFEB using this rabbit polyclonal antibody, Anti-TFEB Antibody validated for use in western blotting.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Qualité

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TFEB in 15 µg of A549 cell lysate.

Description de la cible

~57 kDa observed. Uniprot describes two isoforms at ~44 kDa and ~53 kDa Uncharacterized bands may appear in some lysates.

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
A549 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable