8.18204

N-(Trimethylsilyl)imidazole

for synthesis

• Synonyme(s) : N-(Trimethylsilyl)imidazole, TSIM
• Formule empirique (notation de Hill): C₆H₁₂N₂Si
• Numéro CAS: 18156-74-6
• Poids moléculaire : 140.26
• Numéro MDL: MFCD00005280
• Code UNSPSC : 12352103
• Numéro de classement CE : 242-040-3
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Forme: liquid
• Température d'inflammation spontanée: 540 °C (DIN 51794)
• kinematic viscosity: 2.5 cSt(25 °C)
• Point d'ébullition: 212 °C (decomposition)
• Pf: -42 °C
• Température de transition: flash point 66 °C (DIN 51755 Part 1)
• Densité: 0.955-0.959 g/cm³ at 25 °C
• Température de stockage: 2-30°C
• InChI: 1S/C6H12N2Si/c1-9(2,3)8-5-4-7-6-8/h4-6H,1-3H3
• Clé InChI: YKFRUJSEPGHZFJ-UHFFFAOYSA-N

Description

Application

• Sterol Analysis: Describes the use of N-trimethylsilylimidazole for derivatizing sterols to facilitate fast GLC/MS analysis, which can be completed in under 12.5 minutes. This application is significant for analytical chemistry, particularly in sterol analysis (M Giera, F Plossl, F Bracher, 2023).


• Synthesis of Aryl-5-arylideneimidazol-4-ones: Discusses a new method using N-Trimethylsilylimidazole for the synthesis of 2,3-diaryl-5-arylidene-4imidazolones, involving a dehydration reaction of N-substituted α,β-unsaturated carbonyl compounds, which is pertinent to medicinal chemistry (VO Topuzyan, SR Tosunyan, ER Aleksanyan, 2023).


• Preparation of Ionic Liquids: Outlines the synthesis of 1, 3-bis-(3-sulfonic acid) propyl imidazolium ionic liquids using N-trimethylsilylimidazole, illustrating its utility in the development of new ionic liquid frameworks useful in materials science (K Yuan, W Huang, T Zhang, L Lv, Y Wang, Z Zou, 2023).


• Ultrasonic synthesis of stable oil filled microcapsules: This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like ᴅʟ-N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (Source).

Remarque sur l'analyse

Assay (HClO₄): ≥ 97.0 %
Density (d 20 °C/ 4 °C): 0.952 - 0.958
Identity (IR): passes test

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225 - H315 - H319 - H335
• Conseils de prudence: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 42.8 °F - closed cup
• Point d'éclair (°C): 6 °C - closed cup