662041

U-73343

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

• Synonyme(s) : U-73343, 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
• Formule empirique (notation de Hill): C₂₉H₄₂N₂O₃
• Numéro CAS: 142878-12-4
• Poids moléculaire : 466.66
• Numéro MDL: MFCD00211221
• Code UNSPSC : 51111800
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Couleur: off-white
• Solubilité: ethanol: 1 mg/mL; DMSO: 2 mg/mL; chloroform: 200 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: 10-30°C
• InChI: 1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
• Clé InChI: CJHWFIUASFBCKN-ZRJUGLEFSA-N

Description

Description générale

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Actions biochimiques/physiologiques

Cell permeable: yes

Primary Target
Negative control of U-73122 in the inhibition of phospholipase C

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Irritant (B)

Reconstitution

For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.

Autres remarques

Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther.255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther.253, 688.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable