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Key Documents

529577

Sigma-Aldrich

Prealbumin, Human Plasma

Synonyme(s) :

Prealbumin, Human Plasma, Transthyretin, Thyroxine-binding Prealbumin

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.25

Pureté

>95% (SDS-PAGE)

Niveau de qualité

Forme

lyophilized

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze

Solubilité

physiological buffer: soluble

Conditions d'expédition

ambient

Température de stockage

−20°C

Description générale

Native prealbumin from human plasma. Plasma protein with minimal carbohydrate. Found in plasma at about 30 mg/100 ml. Functions in the transport of retinol-binding protein, thyroxine, and vitamin A.
Native prealbumin from human plasma. Plasma protein with minimal carbohydrate. Found in plasma at about 300 mg/100 ml. Functions in the transport of retinol-binding protein, thyroxine and vitamin A.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

Lyophilized from 150 mM NaCl, 50 mM sodium phosphate buffer, pH 7.5.

Notes préparatoires

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.
Please refer to vial label for lot-specific reconstitution volume.

Autres remarques

Blaney, J.M., et al. 1982. J. Am. Chem. Soc.104, 6424.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Christopher L Cioffi et al.
Journal of medicinal chemistry, 64(13), 9010-9041 (2021-06-18)
Dissociation of transthyretin (TTR) tetramers may lead to misfolding and aggregation of proamyloidogenic monomers, which underlies TTR amyloidosis (ATTR) pathophysiology. ATTR is a progressive disease resulting from the deposition of toxic fibrils in tissues that predominantly presents clinically as amyloid
Lidia Ciccone et al.
Nutrients, 15(3) (2023-02-12)
Eicosapentaenoic acid (EPA; 20:5) and docosahexaenoic acid (DHA; 22:6), two omega-3 poly-unsaturated fatty acids (PUFAs), are the main components in oil derived from fish and other marine organisms. EPA and DHA are commercially available as dietary supplements and are considered
Christopher L Cioffi et al.
Journal of medicinal chemistry, 63(19), 11054-11084 (2020-09-04)
Accumulation of cytotoxic lipofuscin bisretinoids may contribute to atrophic age-related macular degeneration (AMD) pathogenesis. Retinal bisretinoid synthesis depends on the influx of serum all-trans-retinol (1) delivered via a tertiary retinol binding protein 4 (RBP4)-transthyretin (TTR)-retinol complex. We previously identified selective
Xiao-Min Ren et al.
Environmental health perspectives, 128(10), 107008-107008 (2020-10-24)
Tetrabromobisphenol A (TBBPA) mono-ether structural analogs, identified as the by-products or transformation products of commercial TBBPA bis-ether derivatives, have been identified as emerging widespread pollutants. However, there is very little information regarding their toxicological effects. We aimed to explore the

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